Immunological recovery and antiretroviral therapy in HIV-1 infection
Potent antiretroviral therapy has dramatically improved the prognosis of patients infected
with HIV-1. Primary and secondary prophylaxis against Pneumocystis carinii …
with HIV-1. Primary and secondary prophylaxis against Pneumocystis carinii …
Where does HIV live?
J Stebbing, B Gazzard, DC Douek - New England Journal of …, 2004 - Mass Medical Soc
This survey of the cellular and anatomical sites of infection by human immunodeficiency
virus (HIV) discusses the mechanisms of attachment of the virus to cells, the cellular …
virus (HIV) discusses the mechanisms of attachment of the virus to cells, the cellular …
The control of HIV after antiretroviral medication pause (CHAMP) study: posttreatment controllers identified from 14 clinical studies
Background HIV posttreatment controllers are rare individuals who start antiretroviral
therapy (ART), but maintain HIV suppression after treatment interruption. The frequency of …
therapy (ART), but maintain HIV suppression after treatment interruption. The frequency of …
Combination anti-HIV-1 antibody therapy is associated with increased virus-specific T cell immunity
Combination antiretroviral therapy (ART) is highly effective in controlling human
immunodeficiency virus (HIV)-1 but requires lifelong medication due to the existence of a …
immunodeficiency virus (HIV)-1 but requires lifelong medication due to the existence of a …
Delay of HIV-1 rebound after cessation of antiretroviral therapy through passive transfer of human neutralizing antibodies
To determine the protective potential of the humoral immune response against HIV-1 in vivo
we evaluated the potency of three neutralizing antibodies (2G12, 2F5 and 4E10) in …
we evaluated the potency of three neutralizing antibodies (2G12, 2F5 and 4E10) in …
HIV rebounds from latently infected cells, rather than from continuing low-level replication
Rapid rebound of plasma viremia in patients after interruption of long-term combination
antiretroviral therapy (cART) suggests persistence of low-level replicating cells or rapid …
antiretroviral therapy (cART) suggests persistence of low-level replicating cells or rapid …
CD4-guided scheduled treatment interruptions compared with continuous therapy for patients infected with HIV-1: results of the Staccato randomised trial
J Ananworanich, A Gayet-Ageron, M Le Braz… - The Lancet, 2006 - thelancet.com
Background Stop** antiretroviral therapy in patients with HIV-1 infection can reduce costs
and side-effects, but carries the risk of increased immune suppression and emergence of …
and side-effects, but carries the risk of increased immune suppression and emergence of …
CD4-guided structured antiretroviral treatment interruption strategy in HIV-infected adults in west Africa (Trivacan ANRS 1269 trial): a randomised trial
C Danel, R Moh, A Minga, A Anzian, O Ba-Gomis… - The Lancet, 2006 - thelancet.com
Background Structured treatment interruptions of highly-active antiretroviral therapy
(HAART) might be particularly relevant for sub-Saharan Africa, where cost-saving strategies …
(HAART) might be particularly relevant for sub-Saharan Africa, where cost-saving strategies …
[HTML][HTML] Next-generation bNAbs for HIV-1 cure strategies
Despite the ability to suppress viral replication using anti-retroviral therapy (ART), HIV-1
remains a global public health problem. Curative strategies for HIV-1 have to target and …
remains a global public health problem. Curative strategies for HIV-1 have to target and …
Limited durability of viral control following treated acute HIV infection
Background Early treatment of acute HIV infection with highly active antiretroviral therapy,
followed by supervised treatment interruption (STI), has been associated with at least …
followed by supervised treatment interruption (STI), has been associated with at least …