Enhancing the therapeutic efficacy of nanoparticles for cancer treatment using versatile targeted strategies

H Tian, T Zhang, S Qin, Z Huang, L Zhou, J Shi… - Journal of hematology & …, 2022 - Springer
Poor targeting of therapeutics leading to severe adverse effects on normal tissues is
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …

Probing and manipulating noncovalent interactions in functional polymeric systems

J Chen, Q Peng, X Peng, H Zhang, H Zeng - Chemical Reviews, 2022 - ACS Publications
Noncovalent interactions, which usually feature tunable strength, reversibility, and
environmental adaptability, have been recognized as driving forces in a variety of biological …

Stimuli-responsive polymeric nanocarriers for drug delivery, imaging, and theragnosis

SS Das, P Bharadwaj, M Bilal, M Barani, A Rahdar… - Polymers, 2020 - mdpi.com
In the past few decades, polymeric nanocarriers have been recognized as promising tools
and have gained attention from researchers for their potential to efficiently deliver bioactive …

Advances in application of azobenzene as a trigger in biomedicine: Molecular design and spontaneous assembly

HB Cheng, S Zhang, J Qi, XJ Liang… - Advanced …, 2021 - Wiley Online Library
Azobenzene is a well‐known derivative of stimulus‐responsive molecular switches and has
shown superior performance as a functional material in biomedical applications. The results …

Recent advances in bioplastics: application and biodegradation

T Narancic, F Cerrone, N Beagan, KE O'Connor - Polymers, 2020 - mdpi.com
The success of oil-based plastics and the continued growth of production and utilisation can
be attributed to their cost, durability, strength to weight ratio, and eight contributions to the …

Stimuli-responsive nano-architecture drug-delivery systems to solid tumor micromilieu: past, present, and future perspectives

HS El-Sawy, AM Al-Abd, TA Ahmed, KM El-Say… - ACS …, 2018 - ACS Publications
The microenvironment characteristics of solid tumors, renowned as barriers that harshly
impeded many drug-delivery approaches, were precisely studied, investigated, categorized …

Harnessing endogenous stimuli for responsive materials in theranostics

AB Cook, P Decuzzi - ACS nano, 2021 - ACS Publications
Materials that respond to endogenous stimuli are being leveraged to enhance
spatiotemporal control in a range of biomedical applications from drug delivery to diagnostic …

Structure‐based varieties of polymeric nanocarriers and influences of their physicochemical properties on drug delivery profiles

R De, MK Mahata, KT Kim - Advanced Science, 2022 - Wiley Online Library
Carriers are equally important as drugs. They can substantially improve bioavailability of
cargos and safeguard healthy cells from toxic effects of certain therapeutics. Recently …

A hypoxia‐responsive albumin‐based nanosystem for deep tumor penetration and excellent therapeutic efficacy

G Yang, SZF Phua, WQ Lim, R Zhang… - Advanced …, 2019 - Wiley Online Library
Uncontrolled cancer cell proliferation, insufficient blood flow, and inadequate endogenous
oxygen lead to hypoxia in tumor tissues. Herein, a unique type of hypoxia‐responsive …

Stimuli-chromism of photoswitches in smart polymers: Recent advances and applications as chemosensors

A Abdollahi, H Roghani-Mamaqani, B Razavi - Progress in Polymer …, 2019 - Elsevier
Light-responsive polymers, especially photochromic ones, are among the most interesting
classes of stimuli-responsive materials. Photochromic polymers can show different stimuli …