Chitosan is a natural polycationic linear polysaccharide derived from chitin. The low
solubility of chitosan in neutral and alkaline solution limits its application. Nevertheless …

Viral infections, in addition to damaging host cells, can compromise the host immune
system, leading to frequent relapse or long-term persistence. Viruses have the capacity to …

Biodegradable chitin is the second-most abundant natural polysaccharide, widely existing in
the exoskeletons of crabs, shrimps, insects, and the cell walls of fungi. Chitosan and …

The presence of a mucus layer that covers the surface of a variety of organs has been
capitalized to develop mucoadhesive dosage forms that remain in the administration site for …

Various properties of chitosan can be customized by thiolation for very specific needs in a
wide range of application areas. Since the discovery of thiolated chitosans, many studies …

The vagina has been considered a potential drug administration route for centuries. Most of
the currently marketed and investigated vaginal formulations are composed with the use of …

The aim of this study was to evaluate the uptake mechanism of thiolated nanostructured lipid
carriers (NLCs). NLCs were decorated with a short-chain polyoxyethylene (10) stearyl ether …

The vaginal delivery of various drugs is well described and its relevance established in
current medical practice. Alongside recent advances and achievements in the fields of …

Combining two or more antiretroviral drugs in one medical product is an interesting but
challenging strategy for develo** topical anti-HIV microbicides. We developed a new …

Vaccination has been recently attracted as one of the most successful medical treatments of
the prevalence of many infectious diseases. Mucosal vaccination has been interested in …