Enantioconvergent catalysis has expanded asymmetric synthesis to new methodologies
able to convert racemic compounds into a single enantiomer. This review covers recent …

Copper-catalyzed enantioselective propargylic substitution has become an increasingly
reliable strategy to construct stereogenic centers over the past two decades. Currently …

Carbon–oxygen bonds are commonplace in organic molecules, including chiral bioactive
compounds; therefore, the development of methods for their construction with simultaneous …

Chiral α-tertiary amines and related azacycles are sought-after compounds for drug
development. Despite progress in the catalytic asymmetric construction of aza-quaternary …

Catalytic asymmetric transformations by dearomatization have developed into a widely
applicable synthetic strategy, but heavily relied on the use of arenes bearing a heteroatom …

The first copper-catalyzed enantioselective [4+ 1] annulation of yne-allylic esters with 1, 3-
dicarbonyl compounds was realized through an elegant remote stereocontrol strategy. The …

Metal-catalyzed propargylic transformations represent a powerful tool in organic synthesis to
achieve new carbon–carbon and carbon–heteroatom bonds. However, detailed knowledge …

Distinct regio-and enantioselectivity control in copper-catalyzed vinylogous and
bisvinylogous propargylic substitution has been accomplished by using a novel chiral N, N …

Catalytic asymmetric propargylic substitution reactions have received phenomenal progress
and applications, but no study focuses on CO2 gas capture and fixation in this area. The …

A propargylic amination approach toward chiral acyclic α-quaternary α-amino ketones is
described. This Cu-catalyzed procedure could be performed open to air using commercially …