Pulmonary arterial hypertension: pathogenesis and clinical management
Pulmonary hypertension is defined as a resting mean pulmonary artery pressure of 25 mm
Hg or above. This review deals with pulmonary arterial hypertension (PAH), a type of …
Hg or above. This review deals with pulmonary arterial hypertension (PAH), a type of …
A global view of pulmonary hypertension
Pulmonary hypertension is a substantial global health issue. All age groups are affected with
rapidly growing importance in elderly people, particularly in countries with ageing …
rapidly growing importance in elderly people, particularly in countries with ageing …
Molecular genetic framework underlying pulmonary arterial hypertension
Pulmonary arterial hypertension (PAH) is a rare, progressive disorder typified by occlusion
of the pulmonary arterioles owing to endothelial dysfunction and uncontrolled proliferation of …
of the pulmonary arterioles owing to endothelial dysfunction and uncontrolled proliferation of …
Pathology and pathobiology of pulmonary hypertension: current insights and future directions
In recent years, major advances have been made in the understanding of the cellular and
molecular mechanisms driving pulmonary vascular remodelling in various forms of …
molecular mechanisms driving pulmonary vascular remodelling in various forms of …
Global pulmonary vascular remodeling in pulmonary hypertension associated with heart failure and preserved or reduced ejection fraction
AU Fayyaz, WD Edwards, JJ Maleszewski, EA Konik… - Circulation, 2018 - Am Heart Assoc
Background: We hypothesized that pulmonary venous hypertension in heart failure (HF)
leads to predominate remodeling of pulmonary veins and that the severity of venous …
leads to predominate remodeling of pulmonary veins and that the severity of venous …
Potential long-term effects of SARS-CoV-2 infection on the pulmonary vasculature: a global perspective
S Halawa, SS Pullamsetti, CRM Bangham… - Nature Reviews …, 2022 - nature.com
The lungs are the primary target of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) infection, with severe hypoxia being the cause of death in the most critical cases …
CoV-2) infection, with severe hypoxia being the cause of death in the most critical cases …
Management of pulmonary arterial hypertension
Pulmonary hypertension (PH) is common and may result from a number of disorders,
including left heart disease, lung disease, and chronic thromboembolic disease. Pulmonary …
including left heart disease, lung disease, and chronic thromboembolic disease. Pulmonary …
Pulmonary vascular remodeling in pulmonary hypertension
RM Tuder - Cell and tissue research, 2017 - Springer
Pulmonary vascular remodeling is the key structural alteration in pulmonary hypertension
and involves changes in the intima, media and adventitia, often with the interplay of …
and involves changes in the intima, media and adventitia, often with the interplay of …
Role of extracellular matrix in the pathogenesis of pulmonary arterial hypertension
T Thenappan, SY Chan… - American Journal of …, 2018 - journals.physiology.org
Pulmonary arterial hypertension (PAH) is characterized by remodeling of the extracellular
matrix (ECM) of the pulmonary arteries with increased collagen deposition, cross-linkage of …
matrix (ECM) of the pulmonary arteries with increased collagen deposition, cross-linkage of …
Endothelial dysfunction in pulmonary hypertension: cause or consequence?
K Kurakula, VFED Smolders, O Tura-Ceide… - Biomedicines, 2021 - mdpi.com
Pulmonary arterial hypertension (PAH) is a rare, complex, and progressive disease that is
characterized by the abnormal remodeling of the pulmonary arteries that leads to right …
characterized by the abnormal remodeling of the pulmonary arteries that leads to right …