Field cancerization was first described in 1953 when pathologic atypia was identified in
clinically normal tissue surrounding oropharyngeal carcinomas. The discovery of mutated …

Introduction Several anti-hypertensive drugs have photosensitizing properties, however it
remains unclear whether long-term users of these drugs are also at increased risk of skin …

UVA accounts for about 95% of the solar ultraviolet (UV) radiation that reaches Earth and
most likely contributes to human skin cancer risk. In contrast to UVB, which comprises the …

Background Exposure to ultraviolet radiation (UVR) is the most important external risk factor
for skin cancer. Outdoor workers, who are exposed to high ambient UVR levels are at …

Actinic keratosis (AK) is a chronic skin disease in which multiple clinical and subclinical
lesions co-exist across large areas of sun-exposed skin, resulting in field cancerisation …

Simple Summary Actinic keratoses (AKs) are extremely common in the elderly population;
they are universally recognized as precursors of invasive squamous cell carcinoma, and …

Actinic keratoses (AKs) represent the earliest stage in the development of squamous cell
carcinoma (SCC) and represent important biomarkers for individuals at risk for development …

Hypertension remains the leading preventable risk factor for stroke and coronary artery
disease, significantly contributing to all-cause global mortality and predisposing patients to …

The epidemiology of actinic keratoses (AKs) reflects their causation by cumulative sun
exposure, with the highest prevalence seen in pale-skinned people living at low latitudes …

Simple Summary By examining evidence from 30 non-randomized studies, we found that
thiazide diuretic users have a higher risk of skin cancer than non-thiazide diuretic users. A …