Neurodegenerative disorders constitute a substantial proportion of neurological diseases
with significant public health importance. The pathophysiology of neurodegenerative …

Nitric oxide (NO) represents a potential wound therapeutic agent due to its ability to regulate
inflammation and eradicate bacterial infections. Two broad strategies exist to utilize NO for …

The normal biochemical reactions in our body, increased exposure to the environment, and
higher levels of dietary xenobiotic's result in the generation of reactive oxygen species …

The healing of cutaneous wounds is dependent on the progression through distinct, yet
overlap** phases of wound healing, including hemostasis, inflammation, proliferation, and …

The control over iron availability is crucial under homeostatic conditions and even more in
the case of an infection. This results from diverse properties of iron: first, iron is an important …

Macrophages and neutrophils play a decisive role in host responses to intracellular bacteria
including the agent of tuberculosis (TB), M ycobacterium tuberculosis as they represent the …

More than 75% of hospital-acquired or nosocomial urinary tract infections are initiated by
urinary catheters, which are used during the treatment of 15–25% of hospitalized patients …

Abstract Melatonin (N‐acetyl‐5‐methoxytryptamine), an indoleamine produced in many
organs including the pineal gland, was initially characterized as a hormone primarily …

Nitric oxide (NO), the smallest signalling molecule known, is produced by three isoforms of
NO synthase (NOS; EC 1.14. 13.39). They all utilize l-arginine and molecular oxygen as …

M1 and M2 macrophage-type responses kill or repair in vivo. The unique ability of
macrophages to make these polar opposite type of responses provides primary host …