Protein design: From the aspect of water solubility and stability

R Qing, S Hao, E Smorodina, D **, A Zalevsky… - Chemical …, 2022 - ACS Publications
Water solubility and structural stability are key merits for proteins defined by the primary
sequence and 3D-conformation. Their manipulation represents important aspects of the …

A physiological perspective on the origin and evolution of photosynthesis

WF Martin, DA Bryant, JT Beatty - FEMS microbiology reviews, 2018 - academic.oup.com
The origin and early evolution of photosynthesis are reviewed from an ecophysiological
perspective. Earth's first ecosystems were chemotrophic, fueled by geological H2 at …

Rewiring photosynthetic electron transport chains for solar energy conversion

JM Lawrence, RM Egan, T Hoefer… - Nature Reviews …, 2023 - nature.com
Photosynthetic organisms have evolved versatile electron transport chains that efficiently
convert solar energy into chemical energy. Researchers can engineer these electron …

De novo design of protein homodimers containing tunable symmetric protein pockets

DR Hicks, MA Kennedy… - Proceedings of the …, 2022 - National Acad Sciences
Function follows form in biology, and the binding of small molecules requires proteins with
pockets that match the shape of the ligand. For design of binding to symmetric ligands …

Bioexcitons by design: How do we get there?

M Reppert - The Journal of Physical Chemistry B, 2023 - ACS Publications
Biological pigment–protein complexes (PPCs) exhibit a remarkable ability to tune the optical
properties of biological excitons (bioexcitons) through specific pigment–protein interactions …

The role of charge-transfer states in energy transfer and dissipation within natural and artificial bacteriochlorophyll proteins

M Wahadoszamen, I Margalit, AM Ara… - Nature …, 2014 - nature.com
Understanding how specific protein environments affect the mechanisms of non-radiative
energy dissipation within densely assembled chlorophylls in photosynthetic protein …

Exploiting chromophore–protein interactions through linker engineering to tune photoinduced dynamics in a biomimetic light-harvesting platform

M Delor, J Dai, TD Roberts, JR Rogers… - Journal of the …, 2018 - ACS Publications
Creating artificial systems that mimic and surpass those found in nature is one of the great
challenges of modern science. In the context of photosynthetic light harvesting, the difficulty …

De novo design of proteins housing excitonically coupled chlorophyll special pairs

NM Ennist, S Wang, MA Kennedy, M Curti… - Nature Chemical …, 2024 - nature.com
Natural photosystems couple light harvesting to charge separation using a 'special pair'of
chlorophyll molecules that accepts excitation energy from the antenna and initiates an …

Engineering excitonically coupled dimers in an artificial protein for light harvesting via computational modeling

M Curti, V Maffeis, LG Teixeira Alves Duarte… - Protein …, 2023 - Wiley Online Library
In photosynthesis, pigment–protein complexes achieve outstanding photoinduced charge
separation efficiencies through a set of strategies in which excited states delocalization over …

How the protein environment can tune the energy, the coupling, and the ultrafast dynamics of interacting chlorophylls: The example of the water-soluble chlorophyll …

E Fresch, E Meneghin, A Agostini… - The journal of …, 2020 - ACS Publications
The interplay between active molecules and the protein environment in light-harvesting
complexes tunes the photophysics and the dynamical properties of pigment–protein …