Blue-light receptors for optogenetics
Sensory photoreceptors underpin light-dependent adaptations of organismal physiology,
development, and behavior in nature. Adapted for optogenetics, sensory photoreceptors …
development, and behavior in nature. Adapted for optogenetics, sensory photoreceptors …
Optophysiology: Illuminating cell physiology with optogenetics
Optogenetics combines light and genetics to enable precise control of living cells, tissues,
and organisms with tailored functions. Optogenetics has the advantages of …
and organisms with tailored functions. Optogenetics has the advantages of …
Genetically-stable engineered optogenetic gene switches modulate spatial cell morphogenesis in two-and three-dimensional tissue cultures
Recent advances in tissue engineering have been remarkable, yet the precise control of
cellular behavior in 2D and 3D cultures remains challenging. One approach to address this …
cellular behavior in 2D and 3D cultures remains challenging. One approach to address this …
Optobiochemistry: genetically encoded control of protein activity by light
Optobiochemical control of protein activities allows the investigation of protein functions in
living cells with high spatiotemporal resolution. Over the last two decades, numerous natural …
living cells with high spatiotemporal resolution. Over the last two decades, numerous natural …
Self-organization of human dorsal-ventral forebrain structures by light induced SHH
Organizing centers secrete morphogens that specify the emergence of germ layers and the
establishment of the body's axes during embryogenesis. While traditional experimental …
establishment of the body's axes during embryogenesis. While traditional experimental …
Synthetic Gene Circuits for Regulation of Next‐Generation Cell‐Based Therapeutics
Arming human cells with synthetic gene circuits enables to expand their capacity to execute
superior sensing and response actions, offering tremendous potential for innovative cellular …
superior sensing and response actions, offering tremendous potential for innovative cellular …
Photoactivatable Cre recombinase 3.0 for in vivo mouse applications
K Morikawa, K Furuhashi, C de Sena-Tomas… - Nature …, 2020 - nature.com
Optogenetic genome engineering tools enable spatiotemporal control of gene expression
and provide new insight into biological function. Here, we report the new version of …
and provide new insight into biological function. Here, we report the new version of …
Light-mediated control of Gene expression in mammalian cells
M Yamada, SC Nagasaki, T Ozawa, I Imayoshi - Neuroscience Research, 2020 - Elsevier
Taking advantage of the recent development of genetically-defined photo-activatable
actuator molecules, cellular functions, including gene expression, can be controlled by …
actuator molecules, cellular functions, including gene expression, can be controlled by …
Slym1 control the color etiolation of leaves by facilitating the decomposition of chlorophyll in tomato
M Cheng, F Meng, F Mo, H Qi, P Wang, X Chen, J Liu… - Plant Science, 2022 - Elsevier
Photosynthesis, as an important biological process of plants, produces organic substances
for plant growth and development. Although the molecular mechanisms of photosynthesis …
for plant growth and development. Although the molecular mechanisms of photosynthesis …
Optogenetic control of endoplasmic reticulum–mitochondria tethering
F Shi, F Kawano, SE Park, S Komazaki… - ACS Synthetic …, 2018 - ACS Publications
The organelle interface emerges as a dynamic platform for a variety of biological responses.
However, their study has been limited by the lack of tools to manipulate their occurrence in …
However, their study has been limited by the lack of tools to manipulate their occurrence in …