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Microfluidic approaches for cancer cell detection, characterization, and separation
This article reviews the recent developments in microfluidic technologies for in vitro cancer
diagnosis. We summarize the working principles and experimental results of key microfluidic …
diagnosis. We summarize the working principles and experimental results of key microfluidic …
Rare cell isolation and analysis in microfluidics
Rare cells are low-abundance cells in a much larger population of background cells.
Conventional benchtop techniques have limited capabilities to isolate and analyze rare cells …
Conventional benchtop techniques have limited capabilities to isolate and analyze rare cells …
ApoStream™, a new dielectrophoretic device for antibody independent isolation and recovery of viable cancer cells from blood
V Gupta, I Jafferji, M Garza, VO Melnikova… - …, 2012 - pubs.aip.org
Isolation and enumeration of circulating tumor cells (CTCs) are used to monitor metastatic
disease progression and guide cancer therapy. However, currently available technologies …
disease progression and guide cancer therapy. However, currently available technologies …
Isolation of circulating tumor cells by dielectrophoresis
Dielectrophoresis (DEP) is an electrokinetic method that allows intrinsic dielectric properties
of suspended cells to be exploited for discrimination and separation. It has emerged as a …
of suspended cells to be exploited for discrimination and separation. It has emerged as a …
Isolation of rare cells from cell mixtures by dielectrophoresis
PRC Gascoyne, J Noshari, TJ Anderson… - …, 2009 - Wiley Online Library
The application of dielectrophoretic field‐flow fractionation (depFFF) to the isolation of
circulating tumor cells (CTCs) from clinical blood specimens was studied using simulated …
circulating tumor cells (CTCs) from clinical blood specimens was studied using simulated …
Antibody-independent isolation of circulating tumor cells by continuous-flow dielectrophoresis
Circulating tumor cells (CTCs) are prognostic markers for the recurrence of cancer and may
carry molecular information relevant to cancer diagnosis. Dielectrophoresis (DEP) has been …
carry molecular information relevant to cancer diagnosis. Dielectrophoresis (DEP) has been …
Detection and isolation of circulating tumor cells: principles and methods
Efforts to improve the clinical management of several cancers include finding better methods
for the quantitative and qualitative analysis of circulating tumor cells (CTCs). However …
for the quantitative and qualitative analysis of circulating tumor cells (CTCs). However …
Correlations between the dielectric properties and exterior morphology of cells revealed by dielectrophoretic field‐flow fractionation
Although dielectrophoresis (DEP) has great potential for addressing clinical cell isolation
problems based on cell dielectric differences, a biological basis for predicting the DEP …
problems based on cell dielectric differences, a biological basis for predicting the DEP …
Interdigitated comb‐like electrodes for continuous separation of malignant cells from blood using dielectrophoresis
In this paper, a method for continuous flow separation of circulating malignant cells from
blood in a microfluidic device using dielectrophoresis is discussed. Separation of MDA231 …
blood in a microfluidic device using dielectrophoresis is discussed. Separation of MDA231 …
Dielectrophoretic manipulation of cancer cells and their electrical characterization
Electromanipulation and electrical characterization of cancerous cells is becoming a topic of
high interest as the results reported to date demonstrate a good differentiation among …
high interest as the results reported to date demonstrate a good differentiation among …