A review of recent advances in benchmark dose methodology

SM Jensen, FM Kluxen, C Ritz - Risk Analysis, 2019 - Wiley Online Library
In this review, recent methodological developments for the benchmark dose (BMD)
methodology are summarized. Specifically, we introduce the advances for the main steps in …

Simultaneous confidence bands for log‐logistic regression with applications in risk assessment

LX Kerns - Biometrical Journal, 2017 - Wiley Online Library
In risk assessment, it is often desired to make inferences on the low dose levels at which a
specific benchmark risk is attained. Applications of simultaneous hyperbolic confidence …

Benchmark profile and inferences for joint-exposure quantal data in quantitative risk assessment

L Kerns - Communications in Statistics-Theory and Methods, 2020 - Taylor & Francis
In risk assessment, it is often desired to make inferences on the minimum dose levels
(benchmark doses or BMDs) at which a specific benchmark risk (BMR) is attained. The …

Simultaneous confidence sets for several effective doses

DM Tompsett, S Biedermann, W Liu - Biometrical Journal, 2018 - Wiley Online Library
Construction of simultaneous confidence sets for several effective doses currently relies on
inverting the Scheffé type simultaneous confidence band, which is known to be …

Multiplicity-Adjusted confidence limits in risk assessment with quantal response data

L Kerns - Journal of Biopharmaceutical Statistics, 2018 - Taylor & Francis
In risk assessment, it is often desired to make inferences on the risk at certain low doses or
on the dose (s) at which a specific benchmark risk (BMR) is attained. At times, dose levels or …

Simultaneous confidence tubes for comparing several multivariate linear regression models

J Peng, W Liu, F Bretz, AJ Hayter - Biometrical Journal, 2022 - Wiley Online Library
Much of the research on multiple comparison and simultaneous inference in the past 60
years or so has been for the comparisons of several population means. Spurrier seems to …

Simultaneous Statistical Inference for Low Dose Risk Estimation with Quantal Data in Benchmark Analysis

A Alsubie - 2014 - library-archives.canada.ca
Risk assessment studies where data are collected to make safe low dose levels of a toxic
compound/agent are challenging as dose-response information is constrained to high dose …

Contributions to Multiple Comparisons Procedures

T Alshammari - 2016 - library-archives.canada.ca
Risk assessment studies, in which human, animal or ecological data are used to set safe low
dose levels of a toxic agent, are challenging as study information is limited to high dose …