Optical coherence elastography–OCT at work in tissue biomechanics

KV Larin, DD Sampson - Biomedical optics express, 2017 - opg.optica.org
Optical coherence elastography (OCE), as the use of OCT to perform elastography has
come to be known, began in 1998, around ten years after the rest of the field of elastography …

Strain and elasticity imaging in compression optical coherence elastography: the two‐decade perspective and recent advances

VY Zaitsev, AL Matveyev, LA Matveev… - Journal of …, 2021 - Wiley Online Library
Quantitative map** of deformation and elasticity in optical coherence tomography has
attracted much attention of researchers during the last two decades. However, despite …

The emergence of optical elastography in biomedicine

BF Kennedy, P Wijesinghe, DD Sampson - Nature Photonics, 2017 - nature.com
Optical elastography, the use of optics to characterize and map the mechanical properties of
biological tissue, involves measuring the deformation of tissue in response to a load. Such …

Optical coherence elastography in ophthalmology

MA Kirby, I Pelivanov, S Song… - … of biomedical optics, 2017 - spiedigitallibrary.org
Optical coherence elastography (OCE) can provide clinically valuable information based on
local measurements of tissue stiffness. Improved light sources and scanning methods in …

Quantitative micro-elastography: imaging of tissue elasticity using compression optical coherence elastography

KM Kennedy, L Chin, RA McLaughlin, B Latham… - Scientific reports, 2015 - nature.com
Probing the mechanical properties of tissue on the microscale could aid in the identification
of diseased tissues that are inadequately detected using palpation or current clinical …

Histological validation of in vivo assessment of cancer tissue inhomogeneity and automated morphological segmentation enabled by Optical Coherence Elastography

AA Plekhanov, MA Sirotkina, AA Sovetsky… - Scientific reports, 2020 - nature.com
We present a non-invasive (albeit contact) method based on Optical Coherence
Elastography (OCE) enabling the in vivo segmentation of morphological tissue constituents …

Review of optical coherence tomography in oncology

J Wang, Y Xu, SA Boppart - Journal of biomedical optics, 2017 - spiedigitallibrary.org
The application of optical coherence tomography (OCT) in the field of oncology has been
prospering over the past decade. OCT imaging has been used to image a broad spectrum of …

OCT-elastography-based optical biopsy for breast cancer delineation and express assessment of morphological/molecular subtypes

EV Gubarkova, AA Sovetsky, VY Zaitsev… - Biomedical optics …, 2019 - opg.optica.org
Application of compressional optical coherence elastography (OCE) for delineation of tumor
and peri-tumoral tissue with simultaneous assessment of morphological/molecular subtypes …

Diagnostic accuracy of quantitative micro-elastography for margin assessment in breast-conserving surgery

KM Kennedy, R Zilkens, WM Allen, KY Foo, Q Fang… - Cancer research, 2020 - AACR
Inadequate margins in breast-conserving surgery (BCS) are associated with an increased
likelihood of local recurrence of breast cancer. Currently, approximately 20% of BCS …

Intra-operative spectroscopic assessment of surgical margins during breast conserving surgery

DW Shipp, EA Rakha, AA Koloydenko… - Breast Cancer …, 2018 - Springer
Background In over 20% of breast conserving operations, postoperative pathological
assessment of the excised tissue reveals positive margins, requiring additional surgery …