The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative
agent of coronavirus disease 2019 (COVID-19), was first identified in Eastern Asia (Wuhan …

COVID-19 and the renin-angiotensin system (RAS) are linked by angiotensin-converting
enzyme 2 (ACE2), a key enzyme in RAS that has been validated as a SARS-CoV-2 receptor …

The angiotensin II type 1 receptor (AGTR1) plays an integral role in blood pressure control,
and is implicated in the pathogenesis of hypertension. Polymorphisms within this gene have …

(1) Background: Heart failure (HF) is a complex disease and one of the major causes of
morbidity and mortality in the world. The renin-angiotensin system (RAS) may contribute to …

OBJECTIVE: The role of angiotensin converting enzyme (ACE) gene insertion/deletion (I/D)
polymorphism in early onset coronary artery disease age< 55years (ECAD) is controversial …

The Na+/H+ ion exchanger (NHE) pumps Na+ inward the cell and H+ ion outside the cell.
NHE activity increases in response to a decrease in intracellular pH, and it maintains …

Resistant hypertension, a complex multifactorial hypertensive disease, is triggered by
genetic and environmental factors and involves multiple physiological pathways. Single …

The contribution of angiotensin I–converting enzyme insertion-deletion polymorphism (ACE
I/D) to salt-sensitivity hypertension has been extensively studied by means of salt-loading …

Introduction: The development of left ventricular remodelling after acute myocardial
infarction is a predictor of heart failure and mortality. The purpose of the present study was to …

Background—Angiotensinogen, a key protein in the renin-angiotensin system, plays an
important role in cardiovascular hemostasis. Many studies have examined the association …