Pre-eclampsia
Pre-eclampsia is a life-threatening disease of pregnancy unique to humans and a leading
cause of maternal and neonatal morbidity and mortality. Women who survive pre-eclampsia …
cause of maternal and neonatal morbidity and mortality. Women who survive pre-eclampsia …
SARS-CoV-2 infection during pregnancy and risk of preeclampsia: a systematic review and meta-analysis
Objective To examine the relationship between SARS-CoV-2 infection during pregnancy
and the risk for preeclampsia. Data Sources MEDLINE, Embase, POPLINE, CINAHL …
and the risk for preeclampsia. Data Sources MEDLINE, Embase, POPLINE, CINAHL …
Association between gut microbiota and preeclampsia-eclampsia: a two-sample Mendelian randomization study
P Li, H Wang, L Guo, X Gou, G Chen, D Lin, D Fan… - BMC medicine, 2022 - Springer
Background Several recent observational studies have reported that gut microbiota
composition is associated with preeclampsia. However, the causal effect of gut microbiota …
composition is associated with preeclampsia. However, the causal effect of gut microbiota …
Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy
Ionizable lipid nanoparticles (LNPs) are the most clinically advanced nonviral platform for
mRNA delivery. While they have been explored for applications including vaccines and …
mRNA delivery. While they have been explored for applications including vaccines and …
Clinical tools and biomarkers to predict preeclampsia
Preeclampsia is pregnancy-specific, and significantly contributes to maternal, and perinatal
morbidity and mortality worldwide. An effective predictive test for preeclampsia would …
morbidity and mortality worldwide. An effective predictive test for preeclampsia would …
Local immune recognition of trophoblast in early human pregnancy: controversies and questions
A Moffett, N Shreeve - Nature Reviews Immunology, 2023 - nature.com
The role of the maternal immune system in reproductive success in humans remains
controversial. Here we focus on the events that occur in the maternal decidua during the first …
controversial. Here we focus on the events that occur in the maternal decidua during the first …
Gestational diabetes mellitus and preeclampsia: correlation and influencing factors
Y Yang, N Wu - Frontiers in cardiovascular medicine, 2022 - frontiersin.org
Gestational diabetes mellitus (GDM) and preeclampsia (PE) are common pregnancy
complications with similar risk factors and pathophysiological changes. Evidence from …
complications with similar risk factors and pathophysiological changes. Evidence from …
Causality of genetically determined metabolites on anxiety disorders: a two-sample Mendelian randomization study
G **ao, Q He, L Liu, T Zhang, M Zhou, X Li… - Journal of translational …, 2022 - Springer
Background Although anxiety disorders are one of the most prevalent mental disorders, their
underlying biological mechanisms have not yet been fully elucidated. In recent years …
underlying biological mechanisms have not yet been fully elucidated. In recent years …
Cis P-tau is a central circulating and placental etiologic driver and therapeutic target of preeclampsia
Preeclampsia (PE) is the leading cause of maternal and fetal mortality globally and may
trigger dementia later in life in mothers and their offspring. However, the etiological drivers …
trigger dementia later in life in mothers and their offspring. However, the etiological drivers …
Placenta-tropic VEGF mRNA lipid nanoparticles ameliorate murine pre-eclampsia
Pre-eclampsia is a placental disorder that affects 3–5% of all pregnancies and is a leading
cause of maternal and fetal morbidity worldwide 1, 2. With no drug available to slow disease …
cause of maternal and fetal morbidity worldwide 1, 2. With no drug available to slow disease …