Synaptic effects induced by alcohol

DM Lovinger, M Roberto - 2023 - Springer
Ethanol (EtOH) has effects on numerous cellular molecular targets, and alterations in
synaptic function are prominent among these effects. Acute exposure to EtOH activates or …

Mitochondrial dynamics and psychiatric disorders: The missing link

MP Papageorgiou, MD Filiou - Neuroscience & Biobehavioral Reviews, 2024 - Elsevier
Elucidating the molecular mechanisms of psychopathology is crucial for optimized diagnosis
and treatment. Accumulating literature has underlined how mitochondrial bioenergetics …

Effects of chronic ethanol exposure on neuronal function in the prefrontal cortex and extended amygdala

KE Pleil, EG Lowery-Gionta, NA Crowley, C Li… - …, 2015 - Elsevier
Chronic alcohol consumption and withdrawal leads to anxiety, escalated alcohol drinking
behavior, and alcohol dependence. Alterations in the function of key structures within the …

NPY signaling inhibits extended amygdala CRF neurons to suppress binge alcohol drinking

KE Pleil, JA Rinker, EG Lowery-Gionta… - Nature …, 2015 - nature.com
Binge alcohol drinking is a tremendous public health problem because it leads to the
development of numerous pathologies, including alcohol abuse and anxiety. It is thought to …

The neurophysiological basis of stress and anxiety-comparing neuronal diversity in the bed nucleus of the stria terminalis (BNST) across species

Y van de Poll, Y Cras, TJ Ellender - Frontiers in cellular neuroscience, 2023 - frontiersin.org
The bed nucleus of the stria terminalis (BNST), as part of the extended amygdala, has
become a region of increasing interest regarding its role in numerous human stress-related …

The intersection of stress and reward: BNST modulation of aversive and appetitive states

S Ch'ng, J Fu, RM Brown, SJ McDougall… - Progress in Neuro …, 2018 - Elsevier
The bed nucleus of the stria terminalis (BNST) is widely acknowledged as a brain structure
that regulates stress and anxiety states, as well as aversive and appetitive behaviours. The …

NPY-mediated synaptic plasticity in the extended amygdala prioritizes feeding during starvation

S Dodt, NV Widdershooven, ML Dreisow… - Nature …, 2024 - nature.com
Efficient control of feeding behavior requires the coordinated adjustment of complex
motivational and affective neurocircuits. Neuropeptides from energy-sensing hypothalamic …

Amygdala and bed nucleus of the stria terminalis circuitry: implications for addiction-related behaviors

AM Stamatakis, DR Sparta, JH Jennings… - …, 2014 - Elsevier
Complex motivated behavioral processes, such as those that can go awry following
substance abuse and other neuropsychiatric disorders, are mediated by a distributive …

[HTML][HTML] The role of Neuropeptide Y in fear conditioning and extinction

RO Tasan, D Verma, J Wood, G Lach, B Hörmer… - Neuropeptides, 2016 - Elsevier
While anxiety disorders are the brain disorders with the highest prevalence and constitute a
major burden for society, a considerable number of affected people are still treated …

[HTML][HTML] Neuropeptide regulation of signaling and behavior in the BNST

TL Kash, KE Pleil, CA Marcinkiewcz… - Molecules and cells, 2015 - Elsevier
Recent technical developments have transformed how neuroscientists can probe brain
function. What was once thought to be difficult and perhaps impossible, stimulating a single …