Covariate adjustment in randomized controlled trials: General concepts and practical considerations

K Van Lancker, F Bretz, O Dukes - Clinical Trials, 2024 - journals.sagepub.com
There has been a growing interest in covariate adjustment in the analysis of randomized
controlled trials in past years. For instance, the US Food and Drug Administration recently …

Efficient estimation for staggered rollout designs

J Roth, PHC Sant'Anna - Journal of Political Economy …, 2023 - journals.uchicago.edu
We study estimation of causal effects in staggered-rollout designs—that is, settings where
there is staggered treatment adoption and the timing of treatment is as good as randomly …

[KIRJA][B] A first course in causal inference

P Ding - 2024 - books.google.com
The past decade has witnessed an explosion of interest in research and education in causal
inference, due to its wide applications in biomedical research, social sciences, artificial …

Toward better practice of covariate adjustment in analyzing randomized clinical trials

T Ye, J Shao, Y Yi, Q Zhao - Journal of the American Statistical …, 2023 - Taylor & Francis
In randomized clinical trials, adjustments for baseline covariates at both design and analysis
stages are highly encouraged by regulatory agencies. A recent trend is to use a model …

Covariate-adjusted Fisher randomization tests for the average treatment effect

A Zhao, P Ding - Journal of Econometrics, 2021 - Elsevier
Fisher's randomization test (frt) delivers exact p-values under the strong null hypothesis of
no treatment effect on any units whatsoever and allows for flexible covariate adjustment to …

Machine learning for variance reduction in online experiments

Y Guo, D Coey, M Konutgan, W Li… - Advances in …, 2021 - proceedings.neurips.cc
We consider the problem of variance reduction in randomized controlled trials, through the
use of covariates correlated with the outcome but independent of the treatment. We propose …

Some theoretical foundations for the design and analysis of randomized experiments

L Shi, X Li - Journal of Causal Inference, 2024 - degruyter.com
Neyman's seminal work in 1923 has been a milestone in statistics over the century, which
has motivated many fundamental statistical concepts and methodology. In this review, we …

[PDF][PDF] Design-based uncertainty for quasi-experiments

A Rambachan, J Roth - arxiv preprint arxiv:2008.00602, 2020 - aeaweb.org
This paper develops a design-based theory of uncertainty that is suitable for analyzing quasi-
experimental settings, such as difference-in-differences (DiD). A key feature of our …

Lasso-adjusted treatment effect estimation under covariate-adaptive randomization

H Liu, F Tu, W Ma - Biometrika, 2023 - academic.oup.com
We consider the problem of estimating and inferring treatment effects in randomized
experiments. In practice, stratified randomization, or more generally, covariate-adaptive …

On regression-adjusted imputation estimators of the average treatment effect

Z Lin, F Han - arxiv preprint arxiv:2212.05424, 2022 - arxiv.org
Imputing missing potential outcomes using an estimated regression function is a natural
idea for estimating causal effects. In the literature, estimators that combine imputation and …