Significant experimental, computational, and theoretical work has identified rich structure
within the coordinated activity of interconnected neural populations. An emerging challenge …

Trial-to-trial variability in the execution of movements and motor skills is ubiquitous and
widely considered to be the unwanted consequence of a noisy nervous system. However …

Highlights•Preparatory activity is a neural correlate of motor planning.•Multiple brain areas
cooperate to maintain preparatory activity.•Preparatory activity sets network activity to an …

Neural populations can change the computation they perform on very short timescales.
Although such flexibility is common, the underlying computational strategies at the …

Neural circuits must perform computations and then selectively output the results to other
circuits. Yet synapses do not change radically at millisecond timescales. A key question then …

Individual differences in motor learning ability are widely acknowledged, yet little is known
about the factors that underlie them. Here we explore whether movement-to-movement …

Abstract The exploits of Martina Navratilova and Roger Federer represent the pinnacle of
motor learning. However, when considering the range and complexity of the processes that …

It remains an open question how neural responses in motor cortex relate to movement. We
explored the hypothesis that motor cortex reflects dynamics appropriate for generating …

Neural activity is often described in terms of population-level factors extracted from the
responses of many neurons. Factors provide a lower-dimensional description with the aim of …

Neural mechanisms that support flexible sensorimotor computations are not well
understood. In a dynamical system whose state is determined by interactions among …