Structure, function, and regulation of thioesterases

CMD Swarbrick, JD Nanson, EI Patterson… - Progress in Lipid …, 2020 - Elsevier
Thioesterases are present in all living cells and perform a wide range of important biological
functions by catalysing the cleavage of thioester bonds present in a diverse array of cellular …

Lipid Peroxidation-Related Redox Signaling in Osteosarcoma

S Borović Šunjić, M Jaganjac, J Vlainić… - International Journal of …, 2024 - mdpi.com
Oxidative stress and lipid peroxidation play important roles in numerous physiological and
pathological processes, while the bioactive products of lipid peroxidation, lipid …

Amyloid fibril formation, structure and domain swap** of acyl‐coenzyme A thioesterase‐7

M Kumar, SL Teakel, C Swarbrick… - The FEBS …, 2023 - Wiley Online Library
Acyl‐coenzyme A thioesterase (Acot) enzymes are involved in a broad range of essential
intracellular roles including cell signalling, lipid metabolism, inflammation and the opening …

ACOT7 promotes retinoblastoma resistance to vincristine by regulating fatty acid metabolism reprogramming

C Li, K Dong, Y Zhuang, Z Luo, D Qiu, Y Luo, J Li… - Heliyon, 2024 - cell.com
The rate of vincristine (VCR) resistance in the treatment of retinoblastoma (RB) is relatively
high, and the exact role and mechanism of autophagy and fatty acid (FA) metabolism in RB …

Structural basis for disulphide-CoA inhibition of a butyryl-CoA hexameric thioesterase

Y Khandokar, P Srivastava, S Raidal, S Sarker… - Journal of Structural …, 2020 - Elsevier
Acyl-coenzyme A thioesterases (ACTs) catalyse the hydrolysis of thioester bonds between
fatty-acyl chains and coenzyme A (CoA), producing a free fatty-acyl chain and CoA. These …

[BOOK][B] Les Proteïnes regulades per glucosa acoblen la reprogramació metabòlica i l'anèrgia tumoral en la progressió metastàtica del càncer de mama

N Santana Codina - 2014 - ddd.uab.cat
El desenvolupament de la capacitat metastàtica és deguda a l'adquisició de característiques
específiques que acompanyen a la cèl· lula tumoral durant la progressió tumoral, tant en el …