Human organoids in basic research and clinical applications

XY Tang, S Wu, D Wang, C Chu, Y Hong… - Signal transduction and …, 2022 - nature.com
Organoids are three-dimensional (3D) miniature structures cultured in vitro produced from
either human pluripotent stem cells (hPSCs) or adult stem cells (AdSCs) derived from …

Ulcerative colitis: understanding its cellular pathology could provide insights into novel therapies

A Kaur, P Goggolidou - Journal of inflammation, 2020 - Springer
Dynamic interactions between the gastrointestinal epithelium and the mucosal immune
system normally contribute to ensuring intestinal homeostasis and optimal …

Beyond the brain: peripheral interactions after traumatic brain injury

SJ McDonald, JM Sharkey, M Sun… - Journal of …, 2020 - liebertpub.com
Traumatic brain injury (TBI) is a leading cause of death and disability, and there are currently
no pharmacological treatments known to improve patient outcomes. Unquestionably …

IgG and Fcγ receptors in intestinal immunity and inflammation

T Castro-Dopico, MR Clatworthy - Frontiers in immunology, 2019 - frontiersin.org
Fcγ receptors (FcγR) are cell surface glycoproteins that mediate cellular effector functions of
immunoglobulin G (IgG) antibodies. Genetic variation in FcγR genes can influence …

Origin and propagation of human gastric slow-wave activity defined by high-resolution map**

G O'Grady, P Du, LK Cheng… - American Journal …, 2010 - journals.physiology.org
Slow waves coordinate gastric motility, and abnormal slow-wave activity is thought to
contribute to motility disorders. The current understanding of normal human gastric slow …

Current applications of intestinal organoids: a review

T **ang, J Wang, H Li - Stem Cell Research & Therapy, 2024 - Springer
In the past decade, intestinal organoid technology has paved the way for reproducing tissue
or organ morphogenesis during intestinal physiological processes in vitro and studying the …

Recent advances in cell‐based in vitro models to recreate human intestinal inflammation

MH Macedo, M Dias Neto, L Pastrana… - Advanced …, 2023 - Wiley Online Library
Inflammatory bowel disease causes a major burden to patients and healthcare systems,
raising the need to develop effective therapies. Technological advances in cell culture, allied …

Dietary berberine alleviates high carbohydrate diet-induced intestinal damages and improves lipid metabolism in largemouth bass (Micropterus salmoides)

Y Gong, Q Lu, Y Liu, L **, Z Zhang, H Liu, J **… - Frontiers in …, 2022 - frontiersin.org
High carbohydrate diet (HCD) causes metabolism disorder and intestinal damages in
aquaculture fish. Berberine has been applied to improve obesity, diabetes and NAFLD …

[HTML][HTML] SP and KLF transcription factors in cancer metabolism

EJ Orzechowska-Licari, JF LaComb… - International Journal of …, 2022 - mdpi.com
Tumor development and progression depend on reprogramming of signaling pathways that
regulate cell metabolism. Alterations to various metabolic pathways such as glycolysis …

Isolation, purification and characterization of Pueraria lobata polysaccharide and its effects on intestinal function in cyclophosphamide-treated mice

G Cai, C Wu, N Mao, Z Song, L Yu, T Zhu… - International Journal of …, 2022 - Elsevier
This study investigated the structure of acidic Pueraria lobata polysaccharide (a-PLP) and its
bioactive effects on intestinal function in cyclophosphamide (CY)-treated mice. The structure …