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The tubulin code, from molecules to health and disease
ED McKenna, SL Sarbanes… - Annual review of cell …, 2023 - annualreviews.org
Microtubules are essential dynamic polymers composed of α/β-tubulin heterodimers. They
support intracellular trafficking, cell division, cellular motility, and other essential cellular …
support intracellular trafficking, cell division, cellular motility, and other essential cellular …
Unravelling cell migration: defining movement from the cell surface
Cell motility is essential for life and development. Unfortunately, cell migration is also linked
to several pathological processes, such as cancer metastasis. Cells' ability to migrate relies …
to several pathological processes, such as cancer metastasis. Cells' ability to migrate relies …
Distinct fission signatures predict mitochondrial degradation or biogenesis
Mitochondrial fission is a highly regulated process that, when disrupted, can alter
metabolism, proliferation and apoptosis,–. Dysregulation has been linked to …
metabolism, proliferation and apoptosis,–. Dysregulation has been linked to …
In situ architecture of the ciliary base reveals the stepwise assembly of intraflagellar transport trains
The cilium is an antenna-like organelle that performs numerous cellular functions, including
motility, sensing, and signaling. The base of the cilium contains a selective barrier that …
motility, sensing, and signaling. The base of the cilium contains a selective barrier that …
iU-ExM: nanoscopy of organelles and tissues with iterative ultrastructure expansion microscopy
Expansion microscopy (ExM) is a highly effective technique for super-resolution
fluorescence microscopy that enables imaging of biological samples beyond the diffraction …
fluorescence microscopy that enables imaging of biological samples beyond the diffraction …
Field-dependent deep learning enables high-throughput whole-cell 3D super-resolution imaging
Single-molecule localization microscopy in a typical wide-field setup has been widely used
for investigating subcellular structures with super resolution; however, field-dependent …
for investigating subcellular structures with super resolution; however, field-dependent …
Isotropic super-resolution light-sheet microscopy of dynamic intracellular structures at subsecond timescales
Y Zhao, M Zhang, W Zhang, Y Zhou, L Chen, Q Liu… - Nature …, 2022 - nature.com
Long-term visualization of the dynamic interactions between intracellular structures
throughout the three-dimensional space of whole live cells is essential to better understand …
throughout the three-dimensional space of whole live cells is essential to better understand …
Enhanced detection of fluorescence fluctuations for high-throughput super-resolution imaging
High-throughput super-resolution (SR) imaging is attractive for rapid and high-precision
profiling in a wide range of biomedical applications. However, current SR methods require …
profiling in a wide range of biomedical applications. However, current SR methods require …
Event-driven acquisition for content-enriched microscopy
A common goal of fluorescence microscopy is to collect data on specific biological events.
Yet, the event-specific content that can be collected from a sample is limited, especially for …
Yet, the event-specific content that can be collected from a sample is limited, especially for …
Food perception promotes phosphorylation of MFFS131 and mitochondrial fragmentation in liver
S Henschke, H Nolte, J Magoley, T Kleele, C Brandt… - Science, 2024 - science.org
Liver mitochondria play a central role in metabolic adaptations to changing nutritional states,
yet their dynamic regulation upon anticipated changes in nutrient availability has remained …
yet their dynamic regulation upon anticipated changes in nutrient availability has remained …