Ivermectin for preventing and treating COVID‐19

M Popp, M Stegemann, MI Metzendorf… - Cochrane Database …, 2021 - cochranelibrary.com
Background Ivermectin, an antiparasitic agent used to treat parasitic infestations, inhibits the
replication of viruses in vitro. The molecular hypothesis of ivermectin's antiviral mode of …

[PDF][PDF] Retracted: meta-analysis of randomized trials of ivermectin to treat SARS-CoV-2 infection

A Hill, A Garratt, J Levi, J Falconer, L Ellis… - Open Forum …, 2021 - academic.oup.com
Ivermectin is an antiparasitic drug being investigated for repurposing against severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). Ivermectin showed in vitro activity …

Infectious Diseases Society of America Guidelines on the treatment and management of patients with COVID-19 (April 2020)

A Bhimraj, RL Morgan, AH Shumaker… - Clinical infectious …, 2024 - academic.oup.com
Background There are many pharmacologic therapies that are being used or considered for
treatment of coronavirus disease 2019 (COVID-19). There is a need for frequently updated …

[HTML][HTML] ESCMID COVID-19 living guidelines: drug treatment and clinical management

M Bartoletti, O Azap, A Barac, L Bussini… - Clinical microbiology …, 2022 - Elsevier
Abstract Scope In January 2021, the ESCMID Executive Committee decided to launch a new
initiative to develop ESCMID guidelines on several COVID-19-related issues, including …

Effect of higher-dose ivermectin for 6 days vs placebo on time to sustained recovery in outpatients with COVID-19: a randomized clinical trial

S Naggie, DR Boulware, CJ Lindsell, TG Stewart… - JAMA, 2023 - jamanetwork.com
Importance It is unknown whether ivermectin, with a maximum targeted dose of 600 μg/kg,
shortens symptom duration or prevents hospitalization among outpatients with mild to …

Efficacy of ivermectin treatment on disease progression among adults with mild to moderate COVID-19 and comorbidities: the I-TECH randomized clinical trial

SCL Lim, CP Hor, KH Tay, AM Jelani… - JAMA internal …, 2022 - jamanetwork.com
Importance Ivermectin, an inexpensive and widely available antiparasitic drug, is prescribed
to treat COVID-19. Evidence-based data to recommend either for or against the use of …

[HTML][HTML] High-dose ivermectin for early treatment of COVID-19 (COVER study): a randomised, double-blind, multicentre, phase II, dose-finding, proof-of-concept …

D Buonfrate, F Chesini, D Martini… - International journal of …, 2022 - Elsevier
High concentrations of ivermectin demonstrated antiviral activity against SARS-CoV-2 in
vitro. The aim of this study was to assess the safety and efficacy of high-dose ivermectin in …

Infectious Diseases Society of America guidelines on the treatment and management of patients with COVID-19 (September 2022)

A Bhimraj, RL Morgan, AH Shumaker… - Clinical Infectious …, 2024 - academic.oup.com
There are many pharmacologic therapies that are being used or considered for treatment of
coronavirus disease 2019 (COVID-19), with rapidly changing efficacy and safety evidence …

[HTML][HTML] Repositioning Ivermectin for Covid-19 treatment: Molecular mechanisms of action against SARS-CoV-2 replication

ZY Low, AJW Yip, SK Lal - Biochimica et Biophysica Acta (BBA)-Molecular …, 2022 - Elsevier
Ivermectin (IVM) is an FDA approved macrocyclic lactone compound traditionally used to
treat parasitic infestations and has shown to have antiviral potential from previous in-vitro …

Efficacy of COVID-19 treatments: a Bayesian network meta-analysis of randomized controlled trials

C Zhang, H **, YF Wen, G Yin - Frontiers in Public Health, 2021 - frontiersin.org
Background: We provided a comprehensive evaluation of efficacy of available treatments for
coronavirus disease 2019 (COVID-19). Methods: We searched for candidate COVID-19 …