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Insulin-like growth factor 1: a novel treatment for the protection or regeneration of cochlear hair cells
K Yamahara, N Yamamoto, T Nakagawa, J Ito - Hearing Research, 2015 - Elsevier
Sensorineural hearing loss (SNHL) is mainly caused by cochlear hair cell damage. Because
cochlear hair cells and supporting cells lose their ability to proliferate in postnatal mammals …
cochlear hair cells and supporting cells lose their ability to proliferate in postnatal mammals …
A randomized controlled clinical trial of topical insulin-like growth factor-1 therapy for sudden deafness refractory to systemic corticosteroid treatment
T Nakagawa, K Kumakawa, S Usami, N Hato… - BMC medicine, 2014 - Springer
Background To date, no therapeutic option has been established for sudden deafness
refractory to systemic corticosteroids. This study aimed to examine the efficacy and safety of …
refractory to systemic corticosteroids. This study aimed to examine the efficacy and safety of …
Intratympanic steroid therapy as a salvage treatment for sudden sensorineural hearing loss after failure of conventional therapy: a meta-analysis of randomized …
H Li, G Feng, H Wang, Y Feng - Clinical therapeutics, 2015 - Elsevier
Purpose Systemic steroid therapy (SST) for sudden sensorineural hearing loss (SSNHL) is
considered the only effective treatment, but the results are not satisfactory in clinical practice …
considered the only effective treatment, but the results are not satisfactory in clinical practice …
Are intra-tympanically administered steroids effective in patients with sudden deafness? Implications for current clinical practice
PV Vlastarakos, G Papacharalampous… - European Archives of …, 2012 - Springer
Over 60 years since its first report, sudden sensorineural hearing loss (SSNHL) still
represents an ill-explained condition, with potentially devastating effects for the quality of life …
represents an ill-explained condition, with potentially devastating effects for the quality of life …
Hearing changes after intratympanically applied steroids for primary therapy of sudden hearing loss: a meta-analysis using mathematical simulations of drug delivery …
A Liebau, O Pogorzelski, AN Salt… - Otology & …, 2017 - journals.lww.com
Objective: Controlled and uncontrolled studies with primary intratympanic or combined
intratympanic and systemic application of glucocorticosteroids for idiopathic sudden hearing …
intratympanic and systemic application of glucocorticosteroids for idiopathic sudden hearing …
Simultaneous versus subsequent intratympanic dexamethasone for idiopathic sudden sensorineural hearing loss
MK Park, CK Lee, KH Park, JD Lee… - … --head and neck …, 2011 - journals.sagepub.com
Objective. The authors compared the efficacy of simultaneous and subsequent intratympanic
dexamethasone injections for the treatment of idiopathic sudden sensorineural hearing loss …
dexamethasone injections for the treatment of idiopathic sudden sensorineural hearing loss …
Hearing restoration in a deaf animal model with intravenous transplantation of mesenchymal stem cells derived from human umbilical cord blood
MY Choi, SW Yeo, KH Park - Biochemical and biophysical research …, 2012 - Elsevier
OBJECTIVE: This study was performed to confirm the effect of transplantation of human
umbilical cord blood mesenchymal stem cells (UCB-MSCs) on hearing restoration in a …
umbilical cord blood mesenchymal stem cells (UCB-MSCs) on hearing restoration in a …
Hyperbaric oxygen therapy with short duration intratympanic steroid therapy for sudden hearing loss
R Filipo, G Attanasio, M Viccaro, FY Russo… - Acta oto …, 2012 - Taylor & Francis
Conclusion: The excellent tolerability of intratympanic (IT) steroid offers the possibility to use
a high dose, which would appear to be more effective than intravenous (IV) steroid …
a high dose, which would appear to be more effective than intravenous (IV) steroid …
Contribution of intratympanic steroids in the primary treatment of sudden hearing loss
H Demirhan, AR Gökduman, B Hamit… - Acta oto …, 2018 - Taylor & Francis
Objective: The primary objective is to investigate the contribution of intratympanic steroids in
the primary treatment of idiopathic sudden sensorineural hearing loss (ISSNHL). The …
the primary treatment of idiopathic sudden sensorineural hearing loss (ISSNHL). The …
Intratympanic dexamethasone perfusion versus injection for treatment of refractory sudden sensorineural hearing loss
L Li, J Ren, T Yin, W Liu - European archives of oto-rhino-laryngology, 2013 - Springer
Intratympanic steroid treatment for the sudden sensorineural hearing loss (SSNHL) has a
long history and many techniques have been developed. The efficacies are varied in …
long history and many techniques have been developed. The efficacies are varied in …