Apathy is a common condition that involves diminished initiative, diminished interest and
diminished emotional expression or responsiveness. It is highly prevalent in the context of a …

Objectives This narrative review describes the clinical features of apathy and depression in
individuals with neurocognitive disorders (NCDs), with the goal of differentiating the two …

Importance Apathy, characterized by diminished will or initiative and one of the most
prevalent neuropsychiatric symptoms in individuals with Alzheimer disease, is associated …

Objective To compare the utility of the Mild Behavioral Impairment-Checklist (MBI-C) and
Neuropsychiatric Inventory Questionnaire (NPI-Q) to capture NPS in subjective cognitive …

Animal studies over the past two decades have led to extensive advances in our
understanding of pathogenesis of depressive and mood disorders. Among these, rodent …

Apathy is a core symptom in patients with behavioural variant frontotemporal dementia
(bvFTD). It is defined by the observable reduction in goal-directed behaviour, but the …

Acetylcholinesterase inhibitors (ChEI) are the global standard of care for the symptomatic
treatment of Alzheimer's disease (AD) and show significant positive effects in …

Introduction Mild behavioral impairment (MBI) is characterized by later‐life emergence of
neuropsychiatric symptoms. Investigating its relationship with progression to Alzheimer's …

Future research directions include both clinical and basic neuroscience investigations. The
detection of early neuropsychiatric symptoms might be a marker for dementia, and the …

Introduction Mild behavioral impairment (MBI) is a high‐risk state for incident dementia and
comprises five core domains including affective dysregulation, impulse dyscontrol, social …