[HTML][HTML] Skin drug delivery using lipid vesicles: A starting guideline for their development

AJ Guillot, M Martínez-Navarrete, TM Garrigues… - Journal of Controlled …, 2023‏ - Elsevier
Lipid vesicles can provide a cost-effective enhancement of skin drug absorption when
vesicle production process is optimised. It is an important challenge to design the ideal …

[HTML][HTML] Role of the lipid bilayer in outer membrane protein folding in Gram-negative bacteria

JE Horne, DJ Brockwell, SE Radford - Journal of Biological Chemistry, 2020‏ - Elsevier
β-Barrel outer membrane proteins (OMPs) represent the major proteinaceous component of
the outer membrane (OM) of Gram-negative bacteria. These proteins perform key roles in …

A fluorescent membrane tension probe

A Colom, E Derivery, S Soleimanpour, C Tomba… - Nature …, 2018‏ - nature.com
Cells and organelles are delimited by lipid bilayers in which high deformability is essential to
many cell processes, including motility, endocytosis and cell division. Membrane tension is …

Fluorescent probes for lipid rafts: from model membranes to living cells

AS Klymchenko, R Kreder - Chemistry & biology, 2014‏ - cell.com
Membrane microdomains (rafts) remain one of the controversial issues in biophysics.
Fluorescent molecular probes, which make these lipid nanostructures visible through optical …

Mechanical properties of plasma membrane vesicles correlate with lipid order, viscosity and cell density

J Steinkühler, E Sezgin, I Urbančič, C Eggeling… - Communications …, 2019‏ - nature.com
Regulation of plasma membrane curvature and composition governs essential cellular
processes. The material property of bending rigidity describes the energetic cost of …

Switchable nile red-based probe for cholesterol and lipid order at the outer leaflet of biomembranes

OA Kucherak, S Oncul, Z Darwich… - Journal of the …, 2010‏ - ACS Publications
Cholesterol and sphingomyelin form together a highly ordered membrane phase, which is
believed to play important biological functions in plasma membranes of mammalian cells …

[HTML][HTML] Monitoring biophysical properties of lipid membranes by environment-sensitive fluorescent probes

AP Demchenko, Y Mély, G Duportail, AS Klymchenko - Biophysical journal, 2009‏ - cell.com
We review the main trends in the development of fluorescence probes to obtain information
about the structure, dynamics, and interactions in biomembranes. These probes are efficient …

Fluorescent probes based on charge and proton transfer for probing biomolecular environment

VG Pivovarenko, AS Klymchenko - The Chemical Record, 2024‏ - Wiley Online Library
Fluorescent probes for sensing fundamental properties of biomolecular environment, such
as polarity and hydration, help to study assembly of lipids into biomembranes, sensing …

Bright and photostable push-pull pyrene dye visualizes lipid order variation between plasma and intracellular membranes

Y Niko, P Didier, Y Mely, G Konishi, AS Klymchenko - Scientific reports, 2016‏ - nature.com
Imaging lipid organization in cell membranes requires advanced fluorescent probes. Here,
we show that a recently synthesized push-pull pyrene (PA), similarly to popular probe …

Laurdan discerns lipid membrane hydration and cholesterol content

H Orlikowska-Rzeznik, E Krok… - The Journal of …, 2023‏ - ACS Publications
Studies of biological membrane heterogeneity particularly benefit from the use of the
environment-sensitive fluorescent probe Laurdan, for which shifts in the emission, produced …