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[HTML][HTML] The role of copper homeostasis in brain disease
Y An, S Li, X Huang, X Chen, H Shan… - International journal of …, 2022 - mdpi.com
In the human body, copper is an important trace element and is a cofactor for several
important enzymes involved in energy production, iron metabolism, neuropeptide activation …
important enzymes involved in energy production, iron metabolism, neuropeptide activation …
Contemporary epidemiology of chronic liver disease and cirrhosis
Background & Aims Accurate estimates for the contemporary burden of chronic liver disease
(CLD) are vital for setting clinical, research, and policy priorities. We aimed to review the …
(CLD) are vital for setting clinical, research, and policy priorities. We aimed to review the …
A multidisciplinary approach to the diagnosis and management of Wilson disease: Executive summary of the 2022 Practice Guidance on Wilson disease from the …
Copper is an essential metal required for many metalloproteins' function. A fraction of dietary
copper (average 2–5 mg/day) is absorbed by enterocytes in the duodenum and proximal …
copper (average 2–5 mg/day) is absorbed by enterocytes in the duodenum and proximal …
Burden of liver diseases in the world
Liver disease accounts for approximately 2 million deaths per year worldwide, 1 million due
to complications of cirrhosis and 1 million due to viral hepatitis and hepatocellular …
to complications of cirrhosis and 1 million due to viral hepatitis and hepatocellular …
Current and emerging issues in Wilson's disease
EA Roberts, ML Schilsky - New England Journal of Medicine, 2023 - Mass Medical Soc
Current and Emerging Issues in Wilson’s Disease | New England Journal of Medicine Skip to
main content The New England Journal of Medicine homepage Advanced Search SEARCH …
main content The New England Journal of Medicine homepage Advanced Search SEARCH …
Wilson disease
Wilson disease (WD) is a potentially treatable, inherited disorder of copper metabolism that
is characterized by the pathological accumulation of copper. WD is caused by mutations in …
is characterized by the pathological accumulation of copper. WD is caused by mutations in …
Wilson's disease and other neurological copper disorders
The copper metabolism disorder Wilson's disease was first defined in 1912. Wilson's
disease can present with hepatic and neurological deficits, including dystonia and …
disease can present with hepatic and neurological deficits, including dystonia and …
[PDF][PDF] The prevalence of Wilson's disease: an update
TD Sandahl, TL Laursen, DE Munk, H Vilstrup… - …, 2020 - Wiley Online Library
Background and Aims In 1984, Scheinberg and Sternlieb estimated the prevalence of
Wilson's disease to be 1: 30,000 based on the limited available data. This suggested a large …
Wilson's disease to be 1: 30,000 based on the limited available data. This suggested a large …
Wilson's disease: update on pathogenesis, biomarkers and treatments
S Shribman, A Poujois, O Bandmann… - Journal of Neurology …, 2021 - jnnp.bmj.com
Wilson's disease is an autosomal–recessive disorder of copper metabolism caused by
mutations in ATP7B and associated with neurological, psychiatric, ophthalmological and …
mutations in ATP7B and associated with neurological, psychiatric, ophthalmological and …
Activation of autophagy, observed in liver tissues from patients with Wilson disease and from ATP7B-deficient animals, protects hepatocytes from copper-induced …
Background & Aims Wilson disease (WD) is an inherited disorder of copper metabolism that
leads to copper accumulation and toxicity in the liver and brain. It is caused by mutations in …
leads to copper accumulation and toxicity in the liver and brain. It is caused by mutations in …