Chemi-and bioluminescence of cyclic peroxides
Bioluminescence is a phenomenon that has fascinated mankind for centuries. Today the
phenomenon and its sibling, chemiluminescence, have impacted society with a number of …
phenomenon and its sibling, chemiluminescence, have impacted society with a number of …
Molecular imaging in living subjects: seeing fundamental biological processes in a new light
TF Massoud, SS Gambhir - Genes & development, 2003 - genesdev.cshlp.org
Morphological observations have driven the course of biology ever since the first
microscope was built in the late sixteenth century. Molecular imaging is a rapidly emerging …
microscope was built in the late sixteenth century. Molecular imaging is a rapidly emerging …
Engineered exosomes for targeted co-delivery of miR-21 inhibitor and chemotherapeutics to reverse drug resistance in colon cancer
Abstract Background 5-Fluorouracil (5-FU) has been commonly prescribed for patients with
colorectal cancer (CRC), but resistance to 5-FU is one of the main reasons for failure in …
colorectal cancer (CRC), but resistance to 5-FU is one of the main reasons for failure in …
Thymoquinone inhibits bone metastasis of breast cancer cells through abrogation of the CXCR4 signaling axis
MK Shanmugam, KS Ahn, A Hsu, CC Woo… - Frontiers in …, 2018 - frontiersin.org
Overexpression of chemokine receptor type 4 (CXCR4) has been found to be associated
with increased cell proliferation, metastasis and also act as an indicator of poor prognosis in …
with increased cell proliferation, metastasis and also act as an indicator of poor prognosis in …
A luciferin analogue generating near-infrared bioluminescence achieves highly sensitive deep-tissue imaging
In preclinical cancer research, bioluminescence imaging with firefly luciferase and d-luciferin
has become a standard to monitor biological processes both in vitro and in vivo. However …
has become a standard to monitor biological processes both in vitro and in vivo. However …
Advances in in vivo bioluminescence imaging of gene expression
▪ Abstract To advance our understanding of biological processes as they occur in living
animals, imaging strategies have been developed and refined that reveal cellular and …
animals, imaging strategies have been developed and refined that reveal cellular and …
Sequence-specific knockdown of EWS-FLI1 by targeted, nonviral delivery of small interfering RNA inhibits tumor growth in a murine model of metastatic Ewing's …
S Hu-Lieskovan, JD Heidel, DW Bartlett, ME Davis… - Cancer research, 2005 - AACR
The development of effective, systemic therapies for metastatic cancer is highly desired. We
show here that the systemic delivery of sequence-specific small interfering RNA (siRNA) …
show here that the systemic delivery of sequence-specific small interfering RNA (siRNA) …
A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors
The vast majority of brain tumors in adults exhibit glial characteristics. Brain tumors in
children are diverse: Many have neuronal characteristics, whereas others have glial …
children are diverse: Many have neuronal characteristics, whereas others have glial …
Quantitative comparison of the sensitivity of detection of fluorescent and bioluminescent reporters in animal models
T Troy, D Jekic-McMullen, L Sambucetti… - Molecular …, 2004 - journals.sagepub.com
Bioluminescent and fluorescent reporters are finding increased use in optical molecular
imaging in small animals. In the work presented here, issues related to the sensitivity of in …
imaging in small animals. In the work presented here, issues related to the sensitivity of in …
In vivo imaging of light-emitting probes
BW Rice, MD Cable, MB Nelson - Journal of biomedical optics, 2001 - spiedigitallibrary.org
In vivo imaging of cells tagged with light-emitting probes, such as firefly luciferase or
fluorescent proteins, is a powerful technology that enables a wide range of biological studies …
fluorescent proteins, is a powerful technology that enables a wide range of biological studies …