Oxidative stress and antioxidants in neurodegenerative disorders

EO Olufunmilayo, MB Gerke-Duncan, RMD Holsinger - Antioxidants, 2023 - mdpi.com
Neurodegenerative disorders constitute a substantial proportion of neurological diseases
with significant public health importance. The pathophysiology of neurodegenerative …

Antioxidant and Anti-Inflammatory Effects of Citrus Flavonoid Hesperetin: Special Focus on Neurological Disorders

A Khan, M Ikram, JR Hahm, MO Kim - Antioxidants, 2020 - mdpi.com
Neurodegenerative disorders have emerged as a serious health issue in the current era.
The most common neurodegenerative disorders are Alzheimer's disease (AD), Parkinson's …

Hesperidin as a neuroprotective agent: a review of animal and clinical evidence

M Hajialyani, M Hosein Farzaei, J Echeverría… - Molecules, 2019 - mdpi.com
Neuroprotection is the preservation of function and networks of neural tissues from damages
caused by various agents, as well as neurodegenerative diseases such as Parkinson's …

Health-promoting effects of the citrus flavanone hesperidin

C Li, H Schluesener - Critical reviews in food science and nutrition, 2017 - Taylor & Francis
Hesperidin, a member of the flavanone group of flavonoids, can be isolated in large
amounts from the rinds of some citrus species. Considering the wide range of …

Acetylcholinesterase inhibitors in the treatment of neurodegenerative diseases and the role of acetylcholinesterase in their pathogenesis

ŁJ Walczak-Nowicka, M Herbet - International journal of molecular …, 2021 - mdpi.com
Acetylcholinesterase (AChE) plays an important role in the pathogenesis of
neurodegenerative diseases by influencing the inflammatory response, apoptosis, oxidative …

Polyphenols: multipotent therapeutic agents in neurodegenerative diseases

KS Bhullar, HPV Rupasinghe - Oxidative medicine and cellular …, 2013 - Wiley Online Library
Aging leads to numerous transitions in brain physiology including synaptic dysfunction and
disturbances in cognition and memory. With a few clinically relevant drugs, a substantial …

Hesperidin and naringin attenuate hyperglycemia-mediated oxidative stress and proinflammatory cytokine production in high fat fed/streptozotocin-induced type 2 …

AM Mahmoud, MB Ashour, A Abdel-Moneim… - Journal of Diabetes and …, 2012 - Elsevier
Abnormal regulation of glucose and impaired carbohydrate utilization that result from a
defective or deficient insulin are the key pathogenic events in type 2 diabetes mellitus …

Preclinical evidence for the pharmacological actions of naringin: a review

S Bharti, N Rani, B Krishnamurthy, DS Arya - Planta medica, 2014 - thieme-connect.com
Naringin, chemically 4′, 5, 7-trihydroxyflavanone-7-rhamnoglucoside, is a major flavanone
glycoside obtained from tomatoes, grapefruits, and many other citrus fruits. It has been …

Neuroprotective effect of hesperidin on aluminium chloride induced Alzheimer's disease in Wistar rats

AJ Thenmozhi, TRW Raja, U Janakiraman… - Neurochemical …, 2015 - Springer
The present study was aimed to evaluate the protective effect of hesperidin (Hes) on
aluminium chloride (AlCl 3) induced neurobehavioral and pathological changes in …

Naringenin: A prospective therapeutic agent for Alzheimer's and Parkinson's disease

A Goyal, A Verma, N Dubey, J Raghav… - Journal of Food …, 2022 - Wiley Online Library
Neurodegenerative disorders (NDs) are a cluster of progressive, severe, and disabling
disorders that affect millions of people worldwide and are on the surge. These disorders are …