Dynamic control of aptamer–ligand activity using strand displacement reactions
J Lloyd, CH Tran, K Wadhwani… - ACS synthetic …, 2018 - ACS Publications
Nucleic acid aptamers are an expandable toolkit of sensors and regulators. To employ
aptamer regulators within nonequilibrium molecular networks, the aptamer–ligand …
aptamer regulators within nonequilibrium molecular networks, the aptamer–ligand …
Building an RNA-based toggle switch using inhibitory RNA aptamers
Synthetic RNA systems offer unique advantages such as faster response, increased
specificity, and programmability compared to conventional protein-based networks. Here …
specificity, and programmability compared to conventional protein-based networks. Here …
Practical differentiation using ultrasensitive molecular circuits
Biological systems compute spatial and temporal gradients with a variety of mechanisms,
some of which have been shown to include integral feedback. In traditional engineering …
some of which have been shown to include integral feedback. In traditional engineering …
A robust molecular network motif for period-doubling devices
Life is sustained by a variety of cyclic processes such as cell division, muscle contraction,
and neuron firing. The periodic signals powering these processes often direct a variety of …
and neuron firing. The periodic signals powering these processes often direct a variety of …
Design of a bistable network using the CRISPR/Cas system
The CRISPR/Cas-based genome editing system has provided a powerful tool for control of
gene activity within cells. Here, we model an experimentally plausible architecture …
gene activity within cells. Here, we model an experimentally plausible architecture …
Engineering LuxR-type quorum sensing proteins for new functions
NA DeLateur - 2019 - dspace.mit.edu
Bacteria communicate information in a process known as quorum sensing, actuating
downstream gene expression based on cell-cell signalling. Cell-cell signalling allows for …
downstream gene expression based on cell-cell signalling. Cell-cell signalling allows for …
[PDF][PDF] Design of a biomolecular bistable network using the CRISPR/Cas system
The CRISPR/Cas-based genome editing system has provided a powerful tool for control of
gene activity within cells. Here, we model an experimentally plausible architecture …
gene activity within cells. Here, we model an experimentally plausible architecture …
[BOOK][B] Design of Robust Feedback Networks From Ultrasensitive Modules
CEC Samaniego - 2017 - search.proquest.com
Synthetic biology promise to provide solutions to many challenges in energy, agriculture,
and health by reprogramming cells to execute new tasks in the host organism. In order to do …
and health by reprogramming cells to execute new tasks in the host organism. In order to do …
Design of Robust Feedback Networks From Ultrasensitive Modules
CE Cuba Samaniego - 2017 - escholarship.org
Synthetic biology promise to provide solutions to many challenges in energy, agriculture,
and health by reprogramming cells to execute new tasks in the host organism. In order to do …
and health by reprogramming cells to execute new tasks in the host organism. In order to do …