Systemic inflammatory disorders resulting from infection, trauma, surgery, and severe
disease conditions pose serious threats to human health leading to organ dysfunction …

Tissue injury triggers complex communication between cells via secreted signaling
molecules such as cytokines and growth factors. Discerning when and where these signals …

Oncolytic viruses (OVs) are emerging cancer immunotherapy. Despite notable successes in
the treatment of some tumors, OV therapy for central nervous system cancers has failed to …

Biosensors first appeared several decades ago to address the need for monitoring
physiological parameters such as oxygen or glucose in biological fluids such as blood. More …

Monitoring activity of single cells has high significance for basic science and diagnostic
applications. Here we describe a reconfigurable microfluidic device for confining single cells …

We developed a cell-culture/biosensor platform consisting of aptamer-modified Au
electrodes integrated with reconfigurable microfluidics for monitoring of transforming growth …

Transplanted stromal cells have demonstrated considerable promise as therapeutic agents
in diverse disease settings. Paracrine signaling can be an important mediator of these …

In this work, we analyze a mass sensing mechanism that relies on self-excited template
dynamics of a simple network of two coupled oscillators, one linear and one nonlinear, to …

Enteric and diarrheal diseases are major causes of childhood illness and death in countries
with develo** economies. Each year, more than half a million kids under the age of five …

Oncolytic virotherapy, utilizing genetically modified viruses to combat cancer and trigger anti-
cancer immune responses, has garnered significant attention in recent years. In our …