Equine asthma: Integrative biologic relevance of a recently proposed nomenclature

S Bond, R Léguillette, EA Richard… - Journal of veterinary …, 2018 - Wiley Online Library
The term “equine asthma” has been proposed as a unifying descriptor of inflammatory
airway disease (IAD), recurrent airway obstruction (RAO), and summer pasture‐associated …

Asthma: the use of animal models and their translational utility

JS Woodrow, MK Sheats, B Cooper, R Bayless - Cells, 2023 - mdpi.com
Asthma is characterized by chronic lower airway inflammation that results in airway
remodeling, which can lead to a permanent decrease in lung function. The pathophysiology …

Upper and lower respiratory tract microbiota in horses: bacterial communities associated with health and mild asthma (inflammatory airway disease) and effects of …

SL Bond, E Timsit, M Workentine, T Alexander… - BMC microbiology, 2017 - Springer
Background The microbial composition of the equine respiratory tract, and differences due to
mild equine asthma (also called Inflammatory Airway Disease (IAD)) have not been …

[HTML][HTML] Mild-moderate equine asthma: A sco** review of evidence supporting the consensus definition

T Kinnison, TA McGilvray, LL Couetil, KC Smith… - The Veterinary …, 2022 - Elsevier
Current consensus defines mild-moderate equine asthma (mEA; previously inflammatory
airway disease) by a hierarchy of indicators of lung pathology: cough, poor performance …

Effect of different doses of inhaled ciclesonide on lung function, clinical signs related to airflow limitation and serum cortisol levels in horses with experimentally …

JP Lavoie, M Bullone, N Rodrigues… - Equine Veterinary …, 2019 - Wiley Online Library
Background Inhaled corticosteroids are effective for the treatment of equine asthma but they
induce cortisol suppression with potential side effects. Objectives To study the efficacy of …

Glucocorticoid treatment in horses with asthma: A narrative review

S Mainguy‐Seers, JP Lavoie - Journal of veterinary internal …, 2021 - Wiley Online Library
Despite substantial research efforts to improve the treatment and outcome of horses with
asthma, glucocorticoids (GC) remain the cornerstone of drug treatment of this prevalent …

Cigarette smoke extract stimulates MMP-2 production in nasal fibroblasts via ROS/PI3K, Akt, and NF-κB signaling pathways

JH Park, JM Shin, HW Yang, TH Kim, SH Lee, HM Lee… - Antioxidants, 2020 - mdpi.com
Cigarette smoke exposure has been shown to be associated with chronic rhinosinusitis and
tissue remodeling. The present study aimed to investigate the effects of cigarette smoke …

Modeling asthma: Pitfalls, promises, and the road ahead

HF Rosenberg, KM Druey - Journal of leukocyte biology, 2018 - academic.oup.com
Asthma is a chronic, heterogeneous, and recurring inflammatory disease of the lower
airways, with exacerbations that feature airway inflammation and bronchial …

Alkaloids from Tetrastigma hemsleyanum and Their Anti-Inflammatory Effects on LPS-Induced RAW264.7 Cells

CY Wang, HJ Jang, YK Han, XD Su, SW Lee, MC Rho… - Molecules, 2018 - mdpi.com
Alkaloids 1–10 were isolated from the aerial parts of Tetrastigma hemsleyanum (APTH) and
obtained from species of the genus Tetrastigma for the first time. The chemical structures of …

Effect of injected dexamethasone on relative cytokine mRNA expression in bronchoalveolar lavage fluid in horses with mild asthma

SL Bond, J Hundt, R Léguillette - BMC veterinary research, 2019 - Springer
Background Mild equine asthma is a common inflammatory airway disease of the horse. The
primary treatment of mild equine asthma is corticosteroids. The purpose of this study was to …