The mammalian nervous system is comprised of a seemingly infinitely complex network of
specialized synaptic connections that coordinate the flow of information through it. The field …

The morphology and molecular composition of synapses provide the structural basis for
synaptic function. This article reviews the electron microscopy of excitatory synapses on …

Herpesviridae comprise a large family of enveloped DNA viruses all of whom employ
orthologs of the same three glycoproteins, gB, gH and gL. Additionally, herpesviruses often …

Entry of herpes simplex virus (HSV) into cells depends upon multiple cell surface receptors
and multiple proteins on the surface of the virion. The cell surface receptors include heparan …

Spermatogenesis is an intriguing but complicated biological process. However, many
studies since the 1960s have focused either on the hormonal events of the hypothalamus …

The cadherin superfamily plays key roles in intercellular adhesion. An emerging intercellular
adhesion system, consisting of nectin and afadin, also has roles in organization of a variety …

Cadherins are Ca2+-dependent cell-cell adhesion molecules that play critical roles in
animal morphogenesis. Various cadherin-related molecules have also been identified …

Chemical synapses are asymmetric intercellular junctions that mediate synaptic
transmission. Synaptic junctions are organized by trans-synaptic cell adhesion molecules …

Understanding how protein–protein interaction networks in the brain give rise to cognitive
functions necessitates their characterization in live animals. However, tools available for this …

A growing body of epidemiologic and experimental data point to chronic bacterial and viral
infections as possible risk factors for neurodegenerative diseases, including Alzheimer's …