Interleukins and associated cytokines serve as the means of communication for innate and
adaptive immune cells as well as non-immune cells and tissues. Thus, interleukins have a …

Fourteen years have passed since nuclear factor-κB (NF-κB) was first shown to serve as a
molecular lynchpin that links persistent infections and chronic inflammation to increased …

The tumor microenvironment (TME) in gastric cancer (GC) has been shown to be important
for tumor control but the specific characteristics for GC are not fully appreciated. We …

Obesity has become a worldwide epidemic, and its prevalence has been projected to grow
by 40% in the next decade. This increasing prevalence has implications for the risk of …

Research on obesity-and diabetes mellitus (DM)-related carcinogenesis has expanded
exponentially since these two diseases were recognized as important risk factors for …

IL‐17 and IL‐22 are tissue‐signaling cytokines that favor protection and regeneration of
barrier organs such as the skin, lung, and gastrointestinal system. Both cytokines share …

The barrier surfaces of the gastrointestinal tract are in constant contact with various
microorganisms. Cytokines orchestrate the mucosal adaptive and innate immune cells in the …

Although discussion of the obesity epidemic had become a cocktail party cliché, its impact
on public health cannot be dismissed. In the past decade, cancer had joined the list of …

Chronic inflammation is linked to the development of multiple cancers, including those of the
colon. Inflammation in the gut induces carcinogenic mutagenesis and promotes colorectal …

Abstract The interleukin-20 (IL-20) subfamily of cytokines comprises IL-19, IL-20, IL-22, IL-24
and IL-26. These cytokines are all members of the larger IL-10 family, but have been …