Cells are equipped with asymmetrically localised and functionally specialised components,
including cytoskeletal structures and organelles. Positioning these components to specific …

Cells generate a highly diverse microtubule network to carry out different activities. This
network is comprised of distinct tubulin isotypes, tubulins with different post-translational …

During animal development, the spatiotemporal properties of molecular events largely
determine the biological outcomes. Conventional gene analysis methods lack the …

Photoswitchable reagents are powerful tools for high-precision studies in cell biology. When
these reagents are globally administered yet locally photoactivated in two-dimensional (2D) …

Microtubule-severing enzymes (MSEs), such as Katanin, Spastin, and Fidgetin play
essential roles in cell division and neurogenesis. They damage the microtubule (MT) lattice …

The cytoskeleton is essential for spatial and temporal organisation of a wide range of
cellular and tissue‐level processes, such as proliferation, signalling, cargo transport …

Dendritic spines, the mushroom-shaped extensions along dendritic shafts of excitatory
neurons, are critical for synaptic function and are one of the first neuronal structures …

Microtubule (MT) severing enzymes Katanin and Spastin cut the MT into smaller fragments
and are being studied extensively using in-vitro experiments due to their crucial role in …

The biology of a cell is the sum of many highly dynamic processes, each orchestrated by a
plethora of proteins and other molecules. Microscopy is an invaluable approach to spatially …

Azobenzene analogues of the tubulin polymerisation inhibitor combretastatin A4 (PSTs)
were previously developed to optically control microtubule dynamics in living systems, with …