The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the
greatest worldwide pandemic since the 1918 flu. The consequences of the coronavirus …

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a positive-sense,
single-stranded RNA virus that causes the potentially lethal Covid-19 respiratory tract …

Background High systolic blood pressure after successful endovascular therapy for acute
ischaemic stroke is associated with increased risk of intraparenchymal haemorrhage …

Peroxisome proliferator-activated receptor gamma (PPARγ) has been implicated in the
pathology of numerous diseases involving diabetes, stroke, cancer, or obesity. It is …

Microglia can transform into proinflammatory/classically activated (M1) or anti-inflammatory/
alternatively activated (M2) phenotypes following environmental signals related to …

Renin angiotensin system (RAS) is an endocrine system widely known for its physiological
roles in electrolyte homeostasis, body fluid volume regulation and cardiovascular control in …

The process of aging includes changes in cellular biology that affect local interactions
between cells and their environments and eventually propagate to systemic levels. In the …

Rationale: Neurogenic hypertension is characterized by an increase in sympathetic activity
and often resistance to drug treatments. We previously reported that it is also associated with …

Neuropsychiatric conditions including depression, anxiety disorders, and cognitive
impairment are prevalent in patients with chronic kidney disease (CKD). These conditions …

The activation of the brain renin-angiotensin system (RAS) plays a pivotal role in the
pathophysiology of cognition. While the brain RAS has been studied before in the context of …