[HTML][HTML] Oxidative stress in the eye and its role in the pathophysiology of ocular diseases

EW Böhm, F Buonfiglio, AM Voigt, P Bachmann, T Safi… - Redox Biology, 2023 - Elsevier
Oxidative stress occurs through an imbalance between the generation of reactive oxygen
species (ROS) and the antioxidant defense mechanisms of cells. The eye is particularly …

Advances in research on immunocyte iron metabolism, ferroptosis, and their regulatory roles in autoimmune and autoinflammatory diseases

L Zeng, K Yang, G Yu, W Hao, X Zhu, A Ge… - Cell Death & …, 2024 - nature.com
Autoimmune diseases commonly affect various systems, but their etiology and pathogenesis
remain unclear. Currently, increasing research has highlighted the role of ferroptosis in …

Oxidative stress and antioxidants in cataract development

B Lee, NA Afshari, PX Shaw - Current Opinion in Ophthalmology, 2024 - journals.lww.com
Oxidative stress is a significant contributor to cataract development, underscoring the
importance of antioxidants in diagnosis and treatment. Notably, GSH depletion, SOD …

The emerging role of nanozymes in ocular antioxidant therapy

B Xue, Y Lu, S Wang, Q **ao, X Luo, Y Wang, X Yan… - Nano Today, 2024 - Elsevier
Oxidative stress significantly contributes to various ocular diseases, necessitating innovative
therapeutic approaches. This manuscript explores nanozymes which are nanomaterials with …

Potential New Target for Dry Eye Disease—Oxidative Stress

J Bu, Y Liu, R Zhang, S Lin, J Zhuang, L Sun, L Zhang… - Antioxidants, 2024 - mdpi.com
Dry eye disease (DED) is a multifactorial condition affecting the ocular surface. It is
characterized by loss of tear film homeostasis and accompanied by ocular symptoms that …

Novel treatments for dry eye syndrome

E Roucaute, M Huertas-Bello, AL Sabater - Current Opinion in …, 2024 - Elsevier
Dry eye syndrome (DES) is a prevalent and multifactorial disease that leads to a self-
perpetuating cycle of inflammation and damage to the ocular surface. This results in …

Lactobacillus fermentum HY7302 Improves Dry Eye Symptoms in a Mouse Model of Benzalkonium Chloride-Induced Eye Dysfunction and Human Conjunctiva …

K Lee, JW Jeong, JJ Shim, HS Hong, JY Kim… - International Journal of …, 2023 - mdpi.com
(1) We investigated the effects of the Lactobacillus fermentum HY7302 (HY7302) in a mouse
model of benzalkonium chloride (BAC)-induced dry eye, and the possibility of using HY7302 …

Research progress on pharmacological effects against liver and eye diseases of flavonoids present in Chrysanthum indicum L., Chrysanthemum morifolium Ramat …

S **ong, J **e, F **ang, J Yu, Y Li, B **a… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Chrysanthemum indicum L., Chrysanthemum morifolium
Ramat., Buddleja officinalis Maxim., and Sophora japonica L. have the effects of “Clearing …

[HTML][HTML] Nanomedicines for Dry Eye Syndrome: Targeting Oxidative Stress with Modern Nanomaterial Strategies

A Krawczyk, SM Stadler, B Strzalka-Mrozik - Molecules, 2024 - mdpi.com
Dry eye syndrome (DES) is a dynamic, chronic disease of the ocular surface and ocular
appendages caused by inflammation. The most common symptoms include redness, itching …

Norepinephrine Attenuates Benzalkonium Chloride-Induced Dry Eye Disease by Regulating the PINK1/Parkin Mitophagy Pathway

H Zhao, W Wang, Y Yang, C Feng, T Lin… - Ocular Immunology and …, 2024 - Taylor & Francis
Background Increased reactive oxygen species (ROS) are involved in the pathological
process of dry eye disease. Our previous results suggested that norepinephrine (NE) has a …