Mammalian dentition consists of teeth that develop as discrete organs. From anterior to
posterior, the dentition is divided into regions of incisor, canine, premolar and molar tooth …

Craniofacial malformations are involved in three fourths of all congenital birth defects in
humans, affecting the development of head, face, or neck. Tremendous progress in the study …

A classic model proposes that the mammalian neocortex is divided into areas early in
neurogenesis, but the molecular mechanisms that generate the area map have been …

A wealth of information has recently become available on the molecular signals that are
required to form and pattern the dentition in the mouse, shedding light on how important …

During vertebrate craniofacial development, neural crest cells (NCCs) contribute much of the
cartilage, bone and connective tissue that make up the develo** head. Although the initial …

Head development in vertebrates involves a complex series of molecular and
morphogenetic events that generate a coordinated pattern of cartilages, bones and nerves …

We present here an analysis of cardiovascular and pharyngeal arch development in mouse
embryos hypomorphic for Fgf8. Previously, we have described the generation of Fgf8 …

In mammals, the first branchial arch (BA1) develops into a number of craniofacial skeletal
elements including the jaws and teeth. Outgrowth and patterning of BA1 during early …

Salivary glands provide an excellent model for the study of epithelial–mesenchymal
interactions and branching morphogenesis. This review will discuss the anatomy of different …

Clefts of the lip and palate (CLP), the major causes of congenital facial malformation
globally, result from failure of fusion of the facial processes during embryogenesis. With a …