Advances and challenges in understanding cerebral toxoplasmosis

D Schlüter, A Barragan - Frontiers in immunology, 2019 - frontiersin.org
Toxoplasma gondii is a widespread parasitic pathogen that infects over one third of the
global human population. The parasite invades and chronically persists in the central …

Toxoplasma gondii Modulates the Host Cell Responses: An Overview of Apoptosis Pathways

N Mammari, MA Halabi, S Yaacoub… - BioMed research …, 2019 - Wiley Online Library
Infection with Toxoplasma gondii has a major implication in public health. Toxoplasma
gondii is an obligate intracellular protozoan parasite that can infect all nucleated cells …

The tick-borne pathogens: an overview of China's situation

Y Luan, J Gou, D Zhong, L Ma, C Yin, M Shu, G Liu… - Acta Parasitologica, 2023 - Springer
Background Ticks are important medical arthropods that can transmit hundreds of
pathogens, such as parasites, bacteria, and viruses, leading to serious public health …

Secreted Effectors Modulating Immune Responses to Toxoplasma gondii

T Tomita, RB Guevara, LM Shah, AY Afrifa, LM Weiss - Life, 2021 - mdpi.com
Toxoplasma gondii is an obligate intracellular parasite that chronically infects a third of
humans. It can cause life-threatening encephalitis in immune-compromised individuals …

Legionella para-effectors target chromatin and promote bacterial replication

D Schator, S Mondino, J Berthelet, C Di Silvestre… - Nature …, 2023 - nature.com
Legionella pneumophila replicates intracellularly by secreting effectors via a type IV
secretion system. One of these effectors is a eukaryotic methyltransferase (RomA) that …

The determinants regulating Toxoplasma gondii bradyzoite development

M Pan, CC Ge, YM Fan, QW **, B Shen… - Frontiers in …, 2022 - frontiersin.org
Toxoplasma gondii is an obligate intracellular zoonotic pathogen capable of infecting almost
all cells of warm-blooded vertebrates. In intermediate hosts, this parasite reproduces …

Arctigenin ameliorates depression-like behaviors in Toxoplasma gondii-infected intermediate hosts via the TLR4/NF-κB and TNFR1/NF-κB signaling pathways

JH Cheng, X Xu, YB Li, XD Zhao, F Aosai… - International …, 2020 - Elsevier
Toxoplasma gondii (T. gondii) is a known neurotropic protozoan that remains in the central
nervous system and induces neuropsychiatric diseases in intermediate hosts. Arctigenin …

Selective host autophagy is induced during the intracellular parasite Toxoplasma gondii infection controlling amino acid levels

MD White, RK Angara, LT Dias, DD Shinde… - Msphere, 2024 - journals.asm.org
Toxoplasma gondii, a widespread parasite, has the ability to infect nearly any nucleated cell
in warm-blooded vertebrates. It is estimated that around 2 billion people globally have been …

Host-directed therapies for malaria: possible applications and lessons from other indications

J Adderley, GE Grau - Current Opinion in Microbiology, 2023 - Elsevier
Highlights•Treatment failure with traditional drugs implores exploration of novel
strategies.•Host-directed therapy has been successful to treat infectious …

From the immune system to mood disorders especially induced by Toxoplasma gondii: CD4+ T cell as a bridge

Q Wang, Y Zhong, N Chen, J Chen - Frontiers in Cellular and Infection …, 2023 - frontiersin.org
Toxoplasma gondii (T. gondii), a ubiquitous and obligatory intracellular protozoa, not only
alters peripheral immune status, but crosses the blood-brain barrier to trigger brain …