Chromatin accessibility profiling by ATAC-seq
The assay for transposase-accessible chromatin using sequencing (ATAC-seq) provides a
simple and scalable way to detect the unique chromatin landscape associated with a cell …
simple and scalable way to detect the unique chromatin landscape associated with a cell …
Transcription factors as readers and effectors of DNA methylation
Recent technological advances have made it possible to decode DNA methylomes at single-
base-pair resolution under various physiological conditions. Many aberrant or differentially …
base-pair resolution under various physiological conditions. Many aberrant or differentially …
Engineering triangular carbon quantum dots with unprecedented narrow bandwidth emission for multicolored LEDs
F Yuan, T Yuan, L Sui, Z Wang, Z ** of human transcription factor footprints
Combinatorial binding of transcription factors to regulatory DNA underpins gene regulation
in all organisms. Genetic variation in regulatory regions has been connected with diseases …
in all organisms. Genetic variation in regulatory regions has been connected with diseases …
Absence of a simple code: how transcription factors read the genome
Transcription factors (TFs) influence cell fate by interpreting the regulatory DNA within a
genome. TFs recognize DNA in a specific manner; the mechanisms underlying this …
genome. TFs recognize DNA in a specific manner; the mechanisms underlying this …
Chromatin accessibility profiling methods
Chromatin accessibility, or the physical access to chromatinized DNA, is a widely studied
characteristic of the eukaryotic genome. As active regulatory DNA elements are generally …
characteristic of the eukaryotic genome. As active regulatory DNA elements are generally …
Epigenetic analysis of cell-free DNA by fragmentomic profiling
Cell-free DNA (cfDNA) fragmentation patterns contain important molecular information
linked to tissues of origin. We explored the possibility of using fragmentation patterns to …
linked to tissues of origin. We explored the possibility of using fragmentation patterns to …
Nascent RNA scaffolds contribute to chromosome territory architecture and counter chromatin compaction
KM Creamer, HJ Kolpa, JB Lawrence - Molecular cell, 2021 - cell.com
Nuclear chromosomes transcribe far more RNA than required to encode protein. Here we
investigate whether non-coding RNA broadly contributes to cytological-scale chromosome …
investigate whether non-coding RNA broadly contributes to cytological-scale chromosome …