Ischemic disorders, such as myocardial infarction, stroke, and peripheral vascular disease,
are the most common causes of debilitating disease and death in westernized cultures. The …

Disorders characterized by ischemia/reperfusion (I/R), such as myocardial infarction, stroke,
and peripheral vascular disease, continue to be among the most frequent causes of …

Neutrophil recruitment is an important early step in controlling tissue infections or injury.
Here, we report that this influx depends on both tissue-resident mast cells and …

The use of various transgenic mouse models and analysis of human tumour biopsies has
shown that bone marrow-derived myeloid cells, such as macrophages, neutrophils …

Purpose Interstitial cystitis/painful bladder syndrome (IC/PBS) is a chronic pain syndrome
and a chronic inflammatory condition prevalent in women that leads to urgency, sleep …

Cardiovascular diseases are known to be the most fatal diseases worldwide.
Ischaemia/reperfusion (I/R) injury is at the centre of the pathology of the most common …

Rosacea is a common skin disease with a high impact on quality of life. Characterized by
erythema, edema, burning pain, immune infiltration, and facial skin fibrosis, rosacea has all …

Anaphylaxis is the systemic and most severe presentation of type I allergy. A number of
conditions were identified that modulate the onset of anaphylaxis such as co‐or …

Because G-protein coupled receptors (GPCRs) continue to represent excellent targets for
the discovery and development of small-molecule therapeutics, it is posited that additional …

The liver fluke, Fasciola hepatica, causes fascioliasis in domestic animals (sheep, cattle), a
global disease that is also an important infection of humans. As soon as the parasite invades …