Direct Cell Radiolabeling for in Vivo Cell Tracking with PET and SPECT Imaging

PJ Gawne, F Man, PJ Blower… - Chemical reviews, 2022 - ACS Publications
The arrival of cell-based therapies is a revolution in medicine. However, its safe clinical
application in a rational manner depends on reliable, clinically applicable methods for …

Imaging immunity in patients with cancer using positron emission tomography

F Hegi-Johnson, S Rudd, RJ Hicks… - NPJ precision …, 2022 - nature.com
Immune checkpoint inhibitors and related molecules can achieve tumour regression, and
even prolonged survival, for a subset of cancer patients with an otherwise dire prognosis …

In vivo Imaging Technologies to Monitor the Immune System

CE McCarthy, JM White, NT Viola… - Frontiers in …, 2020 - frontiersin.org
The past two decades have brought impressive advancements in immune modulation,
particularly with the advent of both cancer immunotherapy and biologic therapeutics for …

[HTML][HTML] Imaging of cell-based therapy using 89Zr-oxine ex vivo cell labeling for positron emission tomography

Y Kurebayashi, PL Choyke, N Sato - Nanotheranostics, 2021 - ncbi.nlm.nih.gov
With the rapid development of anti-cancer cell-based therapies, such as adoptive T cell
therapies using tumor-infiltrating T cells, T cell receptor transduced T cells, and chimeric …

Utility of PET/CT with fluorine-18-fluorodeoxyglucose-labeled autologous leukocytes for diagnosing diabetic foot osteomyelitis in patients with Charcot's …

A Rastogi, A Bhattacharya, M Prakash… - Nuclear Medicine …, 2016 - journals.lww.com
Objective Diabetic foot osteomyelitis (DFO) is difficult to diagnose in the presence of
Charcot's neuroarthropathy (CN) and bone biopsy is not always possible. We aimed to …

Non-invasive approaches in the diagnosis of acute rejection in kidney transplant recipients. Part I. In vivo imaging methods

O Hanssen, P Erpicum, P Lovinfosse… - Clinical kidney …, 2017 - academic.oup.com
Kidney transplantation (KTx) represents the best available treatment for patients with end-
stage renal disease. Still, full benefits of KTx are undermined by acute rejection (AR). The …

[HTML][HTML] Nuclear imaging for immune cell tracking in vivo–Comparison of various cell labeling methods and their application

Ł Kiraga, P Kucharzewska, S Paisey, Ł Cheda… - Coordination chemistry …, 2021 - Elsevier
There is currently great interest in the development of cell-based therapies, particularly
those focused on the idea of exploiting systemically administered immune cells for …

Biodistribution studies for cell therapy products: Current status and issues

Y Kamiyama, Y Naritomi, Y Moriya, S Yamamoto… - Regenerative …, 2021 - Elsevier
Abstract Information on the biodistribution (BD) of cell therapy products (CTPs) is essential
for prediction and assessment of their efficacy and toxicity profiles in non-clinical and clinical …

Clinical and experimental approaches for imaging of acute kidney injury

D Katagiri, F Wang, JC Gore, RC Harris… - Clinical and …, 2021 - Springer
Complex molecular cell dynamics in acute kidney injury and its heterogeneous etiologies in
patient populations in clinical settings have revealed the potential advantages and …

Next generation imaging techniques to define immune topographies in solid tumors

V Pietrobon, A Cesano, F Marincola… - Frontiers in …, 2021 - frontiersin.org
In recent years, cancer immunotherapy experienced remarkable developments and it is
nowadays considered a promising therapeutic frontier against many types of cancer …