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RNA viruses: ROS‐mediated cell death
Reactive oxygen species (ROS) are well known for being both beneficial and deleterious.
The main thrust of this review is to investigate the role of ROS in ribonucleic acid (RNA) virus …
The main thrust of this review is to investigate the role of ROS in ribonucleic acid (RNA) virus …
Alcohol-associated tissue injury: current views on pathophysiological mechanisms
At-risk alcohol use is a major contributor to the global health care burden and leads to
preventable deaths and diseases including alcohol addiction, alcoholic liver disease …
preventable deaths and diseases including alcohol addiction, alcoholic liver disease …
Cellular signaling pathways as plastic, proto-cognitive systems: Implications for biomedicine
Many aspects of health and disease are modeled using the abstraction of a" pathway"—a
set of protein or other subcellular activities with specified functional linkages between them …
set of protein or other subcellular activities with specified functional linkages between them …
TIPS for adults without cirrhosis with chronic mesenteric venous thrombosis and EHPVO refractory to standard‐of‐care therapy
Background and Aims Extrahepatic portal vein occlusion (EHPVO) from portal vein
thrombosis is a rare condition associated with substantial morbidity and mortality. The …
thrombosis is a rare condition associated with substantial morbidity and mortality. The …
The significance of lactoperoxidase system in oral health: Application and efficacy in oral hygiene products
Lactoperoxidase (LPO) present in saliva are an important element of the nonspecific
immune response involved in maintaining oral health. The main role of this enzyme is to …
immune response involved in maintaining oral health. The main role of this enzyme is to …
The Role of CYP2E1 in the Drug Metabolism or Bioactivation in the Brain
WA García-Suástegui… - Oxidative medicine …, 2017 - Wiley Online Library
Organisms have metabolic pathways that are responsible for removing toxic agents. We
always associate the liver as the major organ responsible for detoxification of the body; …
always associate the liver as the major organ responsible for detoxification of the body; …
Oxidative stress responsive transcription factors in cellular signalling transduction mechanisms
Oxidative stress results from the imbalances in the development of reactive oxygen species
(ROS) and antioxidants defence system resulting in tissue injury. A key issue resulting in the …
(ROS) and antioxidants defence system resulting in tissue injury. A key issue resulting in the …
Complement C3 activation regulates the production of tRNA-derived fragments Gly-tRFs and promotes alcohol-induced liver injury and steatosis
F Zhong, Z Hu, K Jiang, B Lei, Z Wu, G Yuan, H Luo… - Cell research, 2019 - nature.com
Complement is known to play a role in alcoholic fatty liver disease (AFLD), but the
underlying mechanisms are poorly understood, thereby constraining the development of a …
underlying mechanisms are poorly understood, thereby constraining the development of a …
Drug–drug interactions between anti-retroviral therapies and drugs of abuse in HIV systems
Introduction: Substance abuse is a common problem among HIV-infected individuals.
Importantly, addictions as well as moderate use of alcohol, smoking, or other illicit drugs …
Importantly, addictions as well as moderate use of alcohol, smoking, or other illicit drugs …
A comprehensive review of cytochrome P450 2E1 for xenobiotic metabolism
Abstract Cytochrome P450 2E1 (CYP2E1) plays a vital role in drug-induced hepatotoxicity
and cancers (eg lung and bladder cancer), since it is responsible for metabolizing a number …
and cancers (eg lung and bladder cancer), since it is responsible for metabolizing a number …