C–H functionalization reactions are playing an increasing role in the preparation and
modification of complex organic molecules, including pharmaceuticals, agrochemicals and …

Radical-involved transition metal (TM) catalysis has greatly enabled new reactivities in
recent decades. Copper-catalyzed radical relay offers enormous potential in C (sp3)–H …

The arylethylamine pharmacophore is conserved across a range of biologically active
natural products and pharmaceuticals, particularly in molecules that act on the central …

As the “chemical chameleon”, sulfonyl-containing compounds and their variants have been
merged with various types of reactions for the efficient construction of diverse molecular …

C–H activation has surfaced as an increasingly powerful tool for molecular sciences, with
notable applications to material sciences, crop protection, drug discovery, and …

The direct functionalization of C (sp3)–H bonds represents one of the most investigated
approaches to develop new synthetic methodology. Among the available strategies for …

Vicinal alkene carboamination is a highly efficient and practical synthetic strategy for the
straightforward preparation of diverse and valuable amine derivatives starting from simple …

Catalytic transformation of ubiquitous C–H bonds into valuable C–N bonds offers an efficient
synthetic approach to construct N-functionalized molecules. Over the last few decades …

Hydrogen atom transfer from a metal hydride (MHAT) has emerged as a powerful, if
puzzling, technique in chemical synthesis. In catalytic MHAT reactions, earth-abundant …

The synergistic control of the SH2 transition states of hydrogen abstraction by polar and
steric effects provides a promising strategy in achieving site-selective C (sp3)–H …