Catheter ablation for atrial fibrillation (AF) has emerged as an important rhythm-control
strategy and is by far the most common cardiac ablation procedure performed worldwide …

Cardiovascular disease is the leading cause of death worldwide. Although investment in
drug discovery and development has been sky-rocketing, the number of approved drugs has …

Importance Atrial fibrillation (AF) can develop following thoracic irradiation. However, the
critical cardiac substructure responsible for AF has not been properly studied. Objective To …

Arrhythmia and sudden cardiac death remain common in repaired tetralogy of Fallot and
affect even those with excellent anatomic repairs. Atrial arrhythmia often has mechanisms …

As the elderly segment of the world population increases, it is critical to understand the
changes in cardiac structure and function during the normal aging process. In this review …

The SCN5A gene encodes the alpha subunit of the main cardiac sodium channel Nav1. 5.
This channel predominates inward sodium current (INa) and plays a critical role in …

P-wave dispersion (PWD, Pd or Pdis) is a noninvasive electrocardiographic (ECG) marker
for atrial remodeling and predictor for atrial fibrillation (AF). PWD is defined as the difference …

Background: The ability to increase heart rate during exercise and other stressors is a key
homeostatic feature of the sinoatrial node (SAN). When the physiological heart rate …

Exercise has substantial health benefits with pleomorphic vascular, metabolic, psychological
and anti-neoplastic actions resulting in improved quality of life and longevity. Despite these …

Sinus node dysfunction, previously known as sick sinus syndrome, describes disorders
related to abnormal conduction and propagation of electrical impulses at the sinoatrial node …