Extracellular vesicles (EVs) are nano-sized, membranous structures secreted into the
extracellular space. They exhibit diverse sizes, contents, and surface markers and are …

The field of extracellular vesicle (EV) research has developed rapidly over the last decade
from the study of fundamental biology to a subject of significant clinical relevance. The …

Current research has demonstrated that extracellular vesicles (EVs) and circulating tumor
cells (CTCs) are very closely related in the process of distant tumor metastasis. Primary …

Tumor-secreted extracellular vesicles (EVs) are critical mediators of intercellular
communication between tumor cells and stromal cells in local and distant …

The mitogen-activated protein kinase (MAPK) signaling pathway is the primary regulatory
module of various cellular processes such as cell proliferation, differentiation, and stress …

Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …

Two broad categories of extracellular vesicles (EVs), exosomes and shed microvesicles
(sMVs), which differ in size distribution as well as protein and RNA profiles, have been …

Extracellular vesicles (EVs) hold great promise as therapeutic modalities due to their
endogenous characteristics, however, further bioengineering refinement is required to …

Alternative splicing is a tightly regulated process whereby non-coding sequences of pre-
mRNA are removed and protein-coding segments are assembled in diverse combinations …

Exosomes (Exos) as drug delivery vehicles have been widely used for cancer
immunotherapy owing to their good biocompatibility, low toxicity, and low immunogenicity …