Streptococcus pneumoniae is an infectious pathogen responsible for millions of deaths
worldwide. Diseases caused by this bacterium are classified as pneumococcal diseases …

Abstract Amidases (EC 3. 5. 1. X) are versatile biocatalysts for synthesis of chiral carboxylic
acids, α-amino acids and amides due to their hydrolytic and acyl transfer activity towards the …

Streptococcus pneumoniae is a main cause of bacterial meningitis globally, with an estimate
of 100,000 cases among children younger than 5 yr (O'Brien et al., 2009). Despite access to …

Streptococcus pneumoniae (pneumococcus) is an important pathogen responsible for acute
invasive and non-invasive infections such as meningitis, sepsis and otitis media, being the …

Penicillin and related antibiotics disrupt cell wall synthesis to induce bacteriolysis. Lysis in
response to these drugs requires the activity of cell wall hydrolases called autolysins, but …

This review is the eighth update of the original article published in 1999 on the application of
Matrix‐assisted laser desorption/ionization mass spectrometry (MALDI) mass spectrometry …

Highlights•Recent results on the structural biology of PG hydrolases reviewed.•Structural
features of PG recognition and regulation in amidases and LTs analysed.•Shared glycan …

Deamination of choline catalyzed by the glycyl radical enzyme choline trimethylamine-lyase
(CutC) has emerged as an important route for the production of trimethylamine, a microbial …

Serving as an exoskeletal scaffold, peptidoglycan is a polymeric macromolecule that is
essential and conserved across all bacteria, yet is absent in mammalian cells; this has made …

Background The use of antimicrobials to treat food animals may result in antimicrobial
residues in foodstuffs of animal origin. The European Medicines Association (EMA) and …