The feasibility of artificial consciousness through the lens of neuroscience

J Aru, ME Larkum, JM Shine - Trends in neurosciences, 2023 - cell.com
Interactions with large language models (LLMs) have led to the suggestion that these
models may soon be conscious. From the perspective of neuroscience, this position is …

Thalamic contributions to the state and contents of consciousness

CJ Whyte, MJ Redinbaugh, JM Shine, YB Saalmann - Neuron, 2024 - cell.com
Consciousness can be conceptualized as varying along at least two dimensions: the global
state of consciousness and the content of conscious experience. Here, we highlight the …

Thalamic deep brain stimulation in traumatic brain injury: a phase 1, randomized feasibility study

ND Schiff, JT Giacino, CR Butson, EY Choi, JL Baker… - Nature medicine, 2023 - nature.com
Converging evidence indicates that impairments in executive function and information-
processing speed limit quality of life and social reentry after moderate-to-severe traumatic …
AI Luppi, JY Hansen, R Adapa, RL Carhart-Harris… - Science …, 2023 - science.org
To understand how pharmacological interventions can exert their powerful effects on brain
function, we need to understand how they engage the brain's rich neurotransmitter …

The non-specific matrix thalamus facilitates the cortical information processing modes relevant for conscious awareness

EJ Müller, BR Munn, MJ Redinbaugh, J Lizier… - Cell Reports, 2023 - cell.com
The neurobiological mechanisms of arousal and anesthesia remain poorly understood.
Recent evidence highlights the key role of interactions between the cerebral cortex and the …

Prefrontal cortex as a key node in arousal circuitry

GA Mashour, D Pal, EN Brown - Trends in neurosciences, 2022 - cell.com
The role of the prefrontal cortex (PFC) in the mechanism of consciousness is a matter of
active debate. Most theoretical and empirical investigations have focused on whether the …

Neuromodulatory control of complex adaptive dynamics in the brain

JM Shine - Interface focus, 2023 - royalsocietypublishing.org
How is the massive dimensionality and complexity of the microscopic constituents of the
nervous system brought under sufficiently tight control so as to coordinate adaptive …

[HTML][HTML] Brain-heart interactions in the neurobiology of consciousness

D Candia-Rivera - Current Research in Neurobiology, 2022 - Elsevier
Recent experimental evidence on patients with disorders of consciousness revealed that
observing brain-heart interactions helps to detect residual consciousness, even in patients …