Signaling pathways and targeted therapies in lung squamous cell carcinoma: mechanisms and clinical trials

Z Niu, R **, Y Zhang, H Li - Signal Transduction and Targeted Therapy, 2022 - nature.com
Lung cancer is the leading cause of cancer-related death across the world. Unlike lung
adenocarcinoma, patients with lung squamous cell carcinoma (LSCC) have not benefitted …

Non-small-cell lung cancer

LEL Hendriks, J Remon, C Faivre-Finn… - Nature Reviews …, 2024 - nature.com
Non-small-cell lung cancer (NSCLC) is one of the most frequent cancer types and is
responsible for the majority of cancer-related deaths worldwide. The management of …

Tislelizumab plus chemotherapy vs chemotherapy alone as first-line treatment for advanced squamous non–small-cell lung cancer: a phase 3 randomized clinical trial

J Wang, S Lu, X Yu, Y Hu, Y Sun, Z Wang… - JAMA …, 2021 - jamanetwork.com
Importance This study demonstrates that tislelizumab in combination with chemotherapy is
associated with improved progression-free survival (PFS) in patients with advanced …

Deep learning for lung cancer prognostication: a retrospective multi-cohort radiomics study

A Hosny, C Parmar, TP Coroller, P Grossmann… - PLoS …, 2018 - journals.plos.org
Background Non-small-cell lung cancer (NSCLC) patients often demonstrate varying clinical
courses and outcomes, even within the same tumor stage. This study explores deep …

[HTML][HTML] Metastatic non-small-cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

S Novello, F Barlesi, R Califano, T Cufer, S Ekman… - Annals of …, 2016 - Elsevier
In 2012, lung cancer was the most frequently diagnosed cancer and the leading cause of
cancer death in male populations. Among females, lung cancer was the leading cause of …

Preferred reporting items for a systematic review and meta-analysis of individual participant data: the PRISMA-IPD statement

LA Stewart, M Clarke, M Rovers, RD Riley… - Jama, 2015 - jamanetwork.com
Importance Systematic reviews and meta-analyses of individual participant data (IPD) aim to
collect, check, and reanalyze individual-level data from all studies addressing a particular …

Chemotherapy and radiotherapy in nasopharyngeal carcinoma: an update of the MAC-NPC meta-analysis

P Blanchard, A Lee, S Marguet, J Leclercq… - The lancet …, 2015 - thelancet.com
Background A previous individual patient data meta-analysis by the Meta-Analysis of
Chemotherapy in Nasopharynx Carcinoma (MAC-NPC) collaborative group to assess the …

Role of radiotherapy fractionation in head and neck cancers (MARCH): an updated meta-analysis

B Lacas, J Bourhis, J Overgaard, Q Zhang… - The Lancet …, 2017 - thelancet.com
Summary Background The Meta-Analysis of Radiotherapy in squamous cell Carcinomas of
Head and neck (MARCH) showed that altered fractionation radiotherapy is associated with …

Treatment of stage I and II non-small cell lung cancer: Diagnosis and management of lung cancer: American College of Chest Physicians evidence-based clinical …

JA Howington, MG Blum, AC Chang, AA Balekian… - Chest, 2013 - Elsevier
Background The treatment of stage I and II non-small cell lung cancer (NSCLC) in patients
with good or low surgical risk is primarily surgical resection. However, this area is …

Adjuvant systemic therapy and adjuvant radiation therapy for stage I to IIIA completely resected non–small-cell lung cancers: American Society of Clinical Oncology …

MG Kris, LE Gaspar, JE Chaft, EB Kennedy… - Journal of Clinical …, 2017 - ascopubs.org
Purpose The panel updated the American Society of Clinical Oncology (ASCO) adjuvant
therapy guideline for resected non–small-cell lung cancers. Methods ASCO convened an …