Recent advances in insulins, insulin pumps, continuous glucose‐monitoring systems, and
control algorithms have resulted in an acceleration of progress in the development of …

Pursuit of a closed-loop artificial pancreas that automatically controls the blood glucose of
individuals with type 1 diabetes has intensified during the past 6years. Here we discuss the …

Background: We present a clinical trial establishing the feasibility of a control-to-range (CTR)
closed-loop system informed by heart rate (HR) and assess the effect of HR information …

Management of patients with type 1 diabetes (T1D) during and after exercise continues to be
a challenge for care providers and patients alike in terms of approach both to insulin therapy …

To provide an understanding of both the preclinical and clinical aspects of closed-loop
artificial pancreas systems, we provide a discussion of this topic as part of this two-part …

The artificial pancreas (AP) is a closed-loop device with the potential to reduce the
complications associated with type 1 diabetes mellitus by maintaining euglycemia in …

Background: Early detection of exercise in individuals with type 1 diabetes mellitus (T1DM)
may allow changes in therapy to prevent hypoglycemia. Currently there is limited experience …

Background: Time-varying dynamics is one of the main issues for achieving safe blood
glucose control in type 1 diabetes mellitus (T1DM) patients. In addition, the typical …

Objectives The preferred countermeasure to avoid exercise-related hypoglycemia was
investigated in a group of patients with type 1 diabetes participating in a stressful event, a …

Automated glucose control in patients with Type 1 diabetes is much-coveted by patients,
relatives and healthcare professionals. It is the expectation that a system for automated …