UVB-induced microvesicle particle release and its effects on the cutaneous microenvironment
TC Frommeyer, MM Gilbert, GV Brittain, T Wu… - Frontiers in …, 2022 - frontiersin.org
Ultraviolet B radiation (UVB) has profound effects on human skin that results in a broad
spectrum of immunological local and systemic responses and is the major cause of skin …
spectrum of immunological local and systemic responses and is the major cause of skin …
Progress in the development of platelet‐activating factor receptor (PAFr) antagonists and applications in the treatment of inflammatory diseases
IK Hyland, RF O'Toole, JA Smith… - ChemMedChem, 2018 - Wiley Online Library
Platelet‐activating factor (PAF) and its receptor (PAFr) have been implicated in a wide range
of diseases and disorders that originate from the activation of inflammatory pathways …
of diseases and disorders that originate from the activation of inflammatory pathways …
A probiotic has differential effects on allergic airway inflammation in A/J and C57BL/6 mice and is correlated with the gut microbiome
The phenotypes of allergic airway diseases are influenced by the interplay between host
genetics and the gut microbiota, which may be modulated by probiotics. We investigated the …
genetics and the gut microbiota, which may be modulated by probiotics. We investigated the …
Endangered lymphocytes: The effects of alloxan and streptozotocin on immune cells in type 1 induced diabetes
LAD Queiroz, JB Assis, JPT Guimarães… - Mediators of …, 2021 - Wiley Online Library
Alloxan (ALX) and streptozotocin (STZ) are extensively used to induce type 1 diabetes (T1D)
in animal models. This study is aimed at evaluating the differences in immune parameters …
in animal models. This study is aimed at evaluating the differences in immune parameters …
Naja annulifera Snake: New insights into the venom components and pathogenesis of envenomation
F Silva-de-Franca, IM Villas-Boas… - PLoS Neglected …, 2019 - journals.plos.org
Background Naja annulifera is a medically important venomous snake occurring in some of
the countries in Sub-Saharan Africa. Accidental bites result in severe coagulation …
the countries in Sub-Saharan Africa. Accidental bites result in severe coagulation …
Experimental allergic airway inflammation impacts gut homeostasis in mice
CM Nascimento, MC Casaro, ER Perez, WR Ribeiro… - Heliyon, 2023 - cell.com
Abstract Background/Aims: Epidemiological data show that there is an important relationship
between respiratory and intestinal diseases. To improve our understanding on the …
between respiratory and intestinal diseases. To improve our understanding on the …
[HTML][HTML] Platelet activating factor receptor antagonists improve the efficacy of experimental chemo-and radiotherapy
Platelet activating factor is a lipid mediator of inflammation, and in recent decades, it has
emerged as an important factor in tumor outcomes. Platelet activating factor acts by specific …
emerged as an important factor in tumor outcomes. Platelet activating factor acts by specific …
Dendritic cells expressing MyD88 molecule are necessary and sufficient for CpG-mediated inhibition of IgE production in vivo
Elevated levels of immunoglobulin E (IgE) are associated with allergies and other
immunological disorders. Sensitization with alum adjuvant favours IgE production while CpG …
immunological disorders. Sensitization with alum adjuvant favours IgE production while CpG …
Leukotriene B4 modulation of murine dendritic cells affects adaptive immunity
MA Pires-Lapa, MM Koga, IA da Silva Jr… - Prostaglandins & Other …, 2019 - Elsevier
Dendritic cells (DCs) link innate and adaptive immunity. The microenvironment generated
during the innate immunity affects DCs and the type of adaptive immunity generated. Lipid …
during the innate immunity affects DCs and the type of adaptive immunity generated. Lipid …
Maternal supplementation with a synbiotic has distinct outcomes on offspring gut microbiota formation in A/J and C57BL/6 mice, differentially affecting airway …
Emerging evidence has shown that the maternal diet influences the microbiota. Our
objective was to elucidate whether synbiotic consumption during the perinatal period …
objective was to elucidate whether synbiotic consumption during the perinatal period …