Tuberculosis (TB) remains one of the deadliest infectious diseases in human history,
prevailing even in the 21st century. The causative agents of TB are represented by a group …

First achieved in 1998 by Cole et al., the complete genome sequence of Mycobacterium
tuberculosis continues to provide an invaluable resource to understand tuberculosis (TB) …

The human-and animal-adapted lineages of the Mycobacterium tuberculosis complex
(MTBC) are thought to have expanded from a common progenitor in Africa. However, the …

The medical and scientific response to emerging and established pathogens is often
severely hampered by ignorance of the genetic determinants of virulence, drug resistance …

The human pathogen Mycobacterium tuberculosis typically causes lung disease but can
also disseminate to other tissues. We identified a M. tuberculosis (Mtb) outbreak presenting …

N2O is an important greenhouse gas influencing global warming, and agricultural land is the
predominant (anthropogenic) source of N2O emissions. Here, we report the high N2O …

Tuberculosis (TB) is still a severe public health problem; the current diagnostic tests have
limitations that delay treatment onset. Lipoarabinomannan (LAM) is a glycolipid that is a …

Tuberculosis, a disease caused by Mycobacterium tuberculosis (Mtb), is a significant health
problem worldwide. Here, we developed a method to detect large insertions and deletions …

Rapid, sensitive, accurate and portable diagnostics are a mainstay of modern medicine.
Tuberculosis is a disease that has been with us since time immemorial and, despite the fact …

Simple Summary Tuberculosis still causes 1.5 million deaths annually and is mainly caused
by Mycobacterium tuberculosis complex strains belonging to three evolutionary modern …